Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.50 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.39 |
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL1335989 | 0.97 | TSHR (0.53) | TSHRACHECYP3A4TDP1ALDH1A1 | |
| Fluoride SCHEMBL4456415 | 0.97 | TSHR (0.53) | TSHRACHECYP3A4TDP1ALDH1A1 | |
| SCHEMBL127631 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL1845749 | 0.78 | TRPA1 (0.44) | TSHRACHECYP3A4TDP1ALDH1A1 | |
| Fluoride SCHEMBL6232004 | 0.74 | TRPA1 (0.46) | TSHRACHECYP3A4ALDH1A1CA1 | |
| Fluoride SCHEMBL946250 | 0.74 | TRPA1 (0.46) | TSHRACHECYP3A4ALDH1A1CA1 | |
| O-Xylene SCHEMBL577141 | 0.73 | TSHR (0.91) | TSHRACHECYP3A4TDP1ALDH1A1 | |
| O-Xylene SCHEMBL15021872 | 0.73 | TSHR (0.91) | TSHRACHECYP3A4TDP1ALDH1A1 | |
| O-Xylene SCHEMBL7935899 | 0.73 | — | — | |
| O-Xylene SCHEMBL577140 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2675785-B1 | INDUSTRIAL METHODS FOR PRODUCING ARYLSULFUR PENTAFLUORIDES | UBE INDUSTRIES (JP) | 2018-04-11 | — | — | EP | disclosed |
| US-9676710-B2 | Industrial methods for producing arylsulfur pentafluorides | UBE INDUSTRIES, LTD. (JP) | 2017-06-13 | — | — | US | disclosed |
| US-9630920-B2 | Industrial methods for producing arylsulfur pentafluorides | UBE INDUSTRIES, LTD. (JP) | 2017-04-25 | — | — | US | disclosed |
| US-9630919-B2 | Industrial methods for producing arylsulfur pentafluorides | UBE INDUSTRIES, LTD. (JP) | 2017-04-25 | — | — | US | disclosed |
| US-20160362366-A1 | Industrial Methods for Producing Arylsulfur Pentafluorides | UBE CORPORATION (JP) | 2016-12-15 | — | — | US | disclosed |
| US-20160362367-A1 | Industrial Methods for Producing Arylsulfur Pentafluorides | UBE CORPORATION (JP) | 2016-12-15 | — | — | US | disclosed |
| US-20160362365-A1 | Industrial Methods for Producing Arylsulfur Pentafluorides | UBE CORPORATION (JP) | 2016-12-15 | — | — | US | disclosed |
| US-9447034-B2 | Industrial methods for producing arylsulfur pentafluorides | UBE INDUSTRIES, LTD. (JP) | 2016-09-20 | — | — | US | disclosed |
| US-20150315139-A1 | Industrial Methods for Producing Arylsulfur Pentafluorides | UBE CORPORATION (JP) | 2015-11-05 | — | — | US | disclosed |
| US-9108910-B2 | Industrial methods for producing arylsulfur pentafluorides | UBE INDUSTRIES, LTD. (JP) | 2015-08-18 | — | — | US | disclosed |
| US-20130324765-A1 | Industrial Methods for Producing Arylsulfur Pentafluorides | UBE INDUSTRIES, LTD. (JP) | 2013-12-05 | — | — | US | disclosed |
| US-20110190511-A1 | Methods For Preparing Fluoroalkyl Arylsulfinyl Compounds And Fluorinated Compounds Thereto | IM&T RESEARCH, INC. (US) | 2011-08-04 | — | — | US | disclosed |
| EP-2323974-A1 | METHODS FOR PREPARING FLUOROALKYL ARYLSULFINYL COMPOUNDS AND FLUORINATED COMPOUNDS THERETO | Ube Industries, Ltd. (JP) | 2011-05-25 | — | — | EP | disclosed |
| US-20100152463-A1 | Methods for Preparing Fluoroalkyl Arylsulfinyl Compounds and Fluorinated Compounds Thereto | IM&T RESEARCH, INC. (US) | 2010-06-17 | — | — | US | disclosed |
| WO-2010022001-A1 | METHODS FOR PREPARING FLUOROALKYL ARYLSULFINYL COMPOUNDS AND FLUORINATED COMPOUNDS THERETO | IM&T RESEARCH, INC. (US) | 2010-02-25 | — | — | WO | disclosed |
| WO-2010014665-A1 | METHODS FOR PRODUCING ARYLSULFUR PENTAFLUORIDES | IM&T RESEARCH, INC. (US) | 2010-02-04 | — | — | WO | disclosed |
| WO-2009114409-A2 | FLUORINATION PROCESSES WITH ARYLSULFUR HALOTETRAFLUORIDES | IM & T RESEARCH, INC. (US) | 2009-09-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130324765-A1 | Industrial Methods for Producing Arylsulfur Pentafluorides | PFAS, ARSA, CYP2F1 | ACHE 949/4885CA2 2975/4885ESR1 4622/4885 |
| US-20100152463-A1 | Methods for Preparing Fluoroalkyl Arylsulfinyl Compounds and Fluorinated Compounds Thereto | PFAS, AGPS, FDPS | ACHE 1499/4885CA2 4597/4885ESR1 4873/4885 |
| US-20150315139-A1 | Industrial Methods for Producing Arylsulfur Pentafluorides | PFAS, ARSA, CYP2F1 | ACHE 949/4885CA2 2975/4885ESR1 4622/4885 |
| US-20160362367-A1 | Industrial Methods for Producing Arylsulfur Pentafluorides | PFAS, ARSA, CYP2F1 | ACHE 949/4885CA2 2975/4885ESR1 4622/4885 |
| US-20110190511-A1 | Methods For Preparing Fluoroalkyl Arylsulfinyl Compounds And Fluorinated Compounds Thereto | PFAS, AGPS, FDPS | ACHE 808/4885CA2 4787/4885ESR1 4667/4885 |
| US-20160362365-A1 | Industrial Methods for Producing Arylsulfur Pentafluorides | PFAS, ARSA, CYP2F1 | ACHE 949/4885CA2 2975/4885ESR1 4622/4885 |
| US-20160362366-A1 | Industrial Methods for Producing Arylsulfur Pentafluorides | PFAS, ARSA, CYP2F1 | ACHE 949/4885CA2 2975/4885ESR1 4622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.