Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1185557 | 0.86 | GPR35 (0.53) | GPR35NPSR1ALDH1A1HTTMET | |
| SCHEMBL27883380 | 0.82 | SIRT6 (0.48) | GPR35ALDH1A1LMNAMAPTERN1 | |
| SCHEMBL23273444 | 0.80 | NPSR1 (0.36) | ARNPSR1ALDH1A1HTTMET | |
| SCHEMBL9747677 | 0.80 | EGFR (0.43) | GPR35NPSR1ALDH1A1HTTLMNA | |
| SCHEMBL5390806 | 0.79 | NPSR1 (0.35) | NPSR1ALDH1A1HTTMETLMNA | |
| SCHEMBL4748764 | 0.78 | ALDH1A1 (0.53) | NPSR1ALDH1A1HTTLMNAMAPT | |
| SCHEMBL31150407 | 0.78 | ALDH1A1 (0.53) | NPSR1ALDH1A1HTTLMNAMAPT | |
| SCHEMBL557153 | 0.77 | VCAM1 (0.46) | NPSR1ALDH1A1HTTMETLMNA | |
| SCHEMBL8770713 | 0.77 | KMT2A (0.42) | NPSR1ALDH1A1HTTMETMAPT | |
| SCHEMBL1316259 | 0.76 | LMNA (0.51) | LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521758-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | Exxonmobil Chemical Patents Inc. (US) | 2005-04-13 | — | — | EP | claimed |
| WO-2004007509-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-01-22 | — | — | WO | claimed |