Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 15/20 | 0.37 |
| ▸ | CA2 known ✓ | P00918 | 15/20 | 0.37 |
| ▸ | CA12 known ✓ | O43570 | 5/20 | 0.37 |
| ▸ | CA4 known ✓ | P22748 | 4/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 14/20 | 0.37 |
| ▸ | CA7 | P43166 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28554168 | 1.00 | RECQL (0.62) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL453765 | 1.00 | RECQL (0.62) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL1232123 | 1.00 | RECQL (0.62) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL3366402 | 1.00 | RECQL (0.62) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL345943 | 1.00 | RECQL (0.62) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL23573612 | 1.00 | RECQL (0.62) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL366628 | 1.00 | RECQL (0.62) | RECQLTSHRGLAHPGDMAPK1 | |
| Water SCHEMBL27888910 | 0.98 | RECQL (0.60) | RECQLTSHRGLAHPGDMAPK1 | |
| SCHEMBL5445742 | 0.96 | RECQL (0.57) | RECQLTSHRGLAHPGDMAPK1 | |
| Potassium Ion SCHEMBL4898353 | 0.96 | RECQL (0.57) | RECQLTSHRGLAHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0427892-B2 | Method of forming a silver image | AGFA GEVAERT (BE) | 2005-04-27 | — | — | EP | disclosed |
| EP-0696515-B1 | Ink jet printing process | AGFA GEVAERT NV (BE) | 1998-12-02 | — | — | EP | disclosed |
| US-5751325-A | WORKING RELATIONSHIP OF A REDUCING AGENT FOR A METAL COMPOUNDAND PHYSICAL NUCLEI THAT CATALYZE THE METAL | AGFA-GEVAERT, N.V. (BE) | 1998-05-12 | — | — | US | disclosed |
| EP-0532094-B1 | Method for the manufacture of a gelatin containing recording material | AGFA GEVAERT NV (BE) | 1997-07-23 | — | — | EP | disclosed |
| EP-0696515-A1 | Ink jet printing process | AGFA-GEVAERT N.V. (BE) | 1996-02-14 | — | — | EP | disclosed |
| EP-0427892-B1 | Spectrally sensitized silver halide emulsions | AGFA GEVAERT NV (BE) | 1994-01-26 | — | — | EP | disclosed |
| US-5264339-A | Photography | AGFA-GEVAERT N.V. (BE) | 1993-11-23 | — | — | US | disclosed |
| EP-0532094-A1 | Method for the manufacture of a gelatin containing recording material | AGFA-GEVAERT N.V. (BE) | 1993-03-17 | — | — | EP | disclosed |
| US-5116722-A | Trinuclear merocyanine dye continaing at least two water solubilzing groups, minimal residual color stain | AGFA-GEVAERT, N.V. (BE) | 1992-05-26 | — | — | US | disclosed |
| EP-0208346-B1 | DIFFUSION TRANSFER REVERSAL PROCESS | AGFA-GEVAERT N.V. (BE) | 1991-11-21 | — | — | EP | disclosed |
| EP-0427892-A1 | Spectrally sensitized silver halide emulsions | AGFA-GEVAERT N.V. (BE) | 1991-05-22 | — | — | EP | disclosed |
| EP-0208346-A2 | Diffusion transfer reversal process | AGFA-GEVAERT N.V. (BE) | 1987-01-14 | — | — | EP | disclosed |
| EP-0000082-B1 | PROCESS FOR IMAGE-WISE MODIFYING THE SURFACE OF AN ETCHABLE SUPPORT AND MATERIAL SUITABLE THEREFOR COMPRISING A COLLOID LAYER CONTAINING POLYMERS WITH OXIME-ESTER GROUPS | AGFA-GEVAERT N.V. (BE) | 1982-07-21 | — | — | EP | disclosed |
| EP-0003860-B1 | METHOD FOR APPLYING A PLURALITY OF SUPERPOSED PHOTOGRAPHIC LAYERS TO A WEB BY CURTAIN COATING | AGFA-GEVAERT N.V. (BE) | 1982-03-24 | — | — | EP | disclosed |
| US-4277559-A | FOR MASKING UNWANTED BLUE ABSORPTION OF MAGENTA DYES WITHOUT PRODUCING EXCESSIVE FOG | AGFA-GEVAERT N.V. (BE) | 1981-07-07 | — | — | US | disclosed |
| US-4233346-A | Method and apparatus for applying a plurality of superposed layers to a web by curtain coating | AGFA-GEVAERT N.V. (BE) | 1980-11-11 | — | — | US | disclosed |
| US-4202697-A | Production of etch-resist colloid and material suitable therefor | AGFA-GEVAERT N.V. (BE) | 1980-05-13 | — | — | US | disclosed |
| EP-0003860-A1 | Method for applying a plurality of superposed photographic layers to a web by curtain coating | AGFA-GEVAERT N.V. (BE) | 1979-09-05 | — | — | EP | disclosed |
| EP-0000082-A1 | Process for image-wise modifying the surface of an etchable support and material suitable therefor comprising a colloid layer containing polymers with oxime-ester groups | AGFA-GEVAERT N.V. (BE) | 1978-12-20 | — | — | EP | disclosed |