Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 2/20 | 0.60 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.54 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.54 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.54 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.54 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.54 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.54 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.54 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PTGER1 | P34995 | 5/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30911087 | 0.81 | MEN1 (0.52) | POLBDUSP3PTPN5PTPN11CTDSP1 | |
| SCHEMBL1699587 | 0.81 | MEN1 (0.52) | POLBDUSP3PTPN5PTPN11CTDSP1 | |
| SCHEMBL2395263 | 0.79 | PTGER1 (0.56) | CXCL8CAMK2AL3MBTL1PTGER1CFD | |
| SCHEMBL5092502 | 0.79 | CFD (0.58) | FABP4FABP5CXCL8ALDH1A1L3MBTL1 | |
| SCHEMBL6241934 | 0.78 | POLB (0.56) | POLBDUSP3PTPN5PTPN11CTDSP1 | |
| SCHEMBL7787950 | 0.77 | FABP4 (0.69) | FABP4FABP5CXCL8CAMK2APTGER1 | |
| SCHEMBL2292252 | 0.76 | TP53 (0.62) | FABP4FABP5ALDH1A1TP53HTT | |
| SCHEMBL29118568 | 0.76 | ALDH1A1 (0.48) | FABP4FABP5POLBDUSP3PTPN5 | |
| SCHEMBL21462276 | 0.76 | L3MBTL1 (0.48) | FABP4FABP5POLBDUSP3PTPN5 | |
| SCHEMBL5664165 | 0.75 | FABP4 (1.00) | FABP4FABP5CXCL8CAMK2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005009104-A2 | BENZOIC AND PHENYL ACETIC ACID DERIVATIVES AS HNF-4 MODULATORS | LIGAND PHARMACUETICALS INCORPORATED (US) | 2005-02-03 | — | — | WO | claimed |