Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 7/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6237772 | 0.82 | MEN1 (0.61) | RAB9ATSHRGAACYP2C19 | |
| SCHEMBL5188945 | 0.77 | TEAD3 (0.52) | GRM5TSHRALDH1A1GAALMNA | |
| SCHEMBL14880554 | 0.77 | ALDH1A1 (0.39) | RAB9ATSHRALDH1A1GAAPOLB | |
| SCHEMBL3795583 | 0.73 | MEN1 (0.69) | RAB9ATSHRALDH1A1GAACYP2C19 | |
| SCHEMBL5235142 | 0.72 | CTSL (0.55) | RAB9AALDH1A1CYP2C19 | |
| SCHEMBL4429612 | 0.71 | NPSR1 (0.60) | RAB9ATSHRALDH1A1CYP2C19LMNA | |
| Sulfuric Acid SCHEMBL21681660 | 0.71 | TSHR (0.71) | TSHRALDH1A1GAAPOLBLMNA | |
| SCHEMBL2850013 | 0.71 | ALDH1A1 (0.70) | TSHRALDH1A1LMNA | |
| SCHEMBL7962074 | 0.71 | SIGMAR1 (0.69) | TSHRALDH1A1LMNA | |
| SCHEMBL17803548 | 0.70 | CARM1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005013909-A2 | NOVEL CATHEPSIN K INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2005-02-17 | — | — | WO | disclosed |