SCHEMBL624586

SCHEMBL624586

COc1ccc(C=C2CCCCC2=O)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.73
EGFR P00533 5/20 0.71
DYRK1A Q13627 3/20 0.63
DYRK1B Q9Y463 3/20 0.63
CLK1 P49759 2/20 0.63
MAPT P10636 4/20 0.61
NPC1 O15118 3/20 0.61
RAB9A P51151 3/20 0.61
HPGD P15428 2/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
ALDH1A1 P00352 6/20 0.60
GAA P10253 1/20 0.60
USP2 O75604 1/20 0.57
AKR1C3 P42330 1/20 0.57
AKR1C1 Q04828 1/20 0.57
KMT2A Q03164 2/20 0.56
HTT P42858 1/20 0.56
MEN1 O00255 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13299359 1.00 CYP1A2 (0.73) CYP1A2EGFRDYRK1ADYRK1BCLK1
SCHEMBL3258032 1.00 CYP1A2 (0.73) CYP1A2EGFRDYRK1ADYRK1BCLK1
SCHEMBL812347 0.97 CYP1A2 (0.78) CYP1A2EGFRDYRK1ADYRK1BCLK1
SCHEMBL1524447 0.97 CYP1A2 (0.78) CYP1A2EGFRDYRK1ADYRK1BCLK1
SCHEMBL809541 0.97 CYP1A2 (0.78) CYP1A2EGFRDYRK1ADYRK1BCLK1
SCHEMBL29506220 0.85 CYP1A2 (0.71) CYP1A2EGFRDYRK1ADYRK1BCLK1
SCHEMBL17693074 0.84 CYP1A2 (1.00) CYP1A2EGFRDYRK1ADYRK1BCLK1
SCHEMBL17077341 0.83 EGFR (1.00) EGFRXDH
SCHEMBL17077342 0.83 EGFR (1.00) EGFRXDH
SCHEMBL3438520 0.82 RAB9A (0.59) CYP1A2EGFRDYRK1ADYRK1BCLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7807856-B2 Process for production of 2-Benzylphenol compound IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 2010-10-05 US claimed
US-20080194882-A1 Process For Production of 2-Benzylphenol Compound IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 2008-08-14 US claimed
EP-1810957-A1 METHOD FOR PRODUCING 2-BENZYLPHENOL COMPOUND Ihara Chemical Industry Co., Ltd. (JP) 2007-07-25 EP claimed
US-7166274-B2 Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds L'OREAL (FR) 2007-01-23 US claimed
US-20040047820-A1 Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds SOCIETE L'OREAL S.A. (FR) 2004-03-11 US claimed
EP-1370232-A2 COSMETIC SOLAR PROTECTION COMPOSITIONS BASED ON A SYNERGIC MIXTURE OF FILTERS AND USES L'OREAL (FR) 2003-12-17 EP claimed
US-6627180-B2 Particles having protection factor UV-APPD and an amino substituted 2-hydroxybenzophenone SOCIETE L'OREAL S.A. (FR) 2003-09-30 US claimed
US-20030152532-A1 SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS SOCIETE L'OREAL S.A. (FR) 2003-08-14 US claimed
EP-1317918-A1 Cosmetic sunscreen compositions based on synergistic filter mixture and their use L'OREAL (FR) 2003-06-11 EP claimed
WO-2002056858-A1 SOLAR PROTECTION COMPOSITIONS L'OREAL (FR) 2002-07-25 WO claimed
WO-2002049597-A2 COSMETIC SOLAR PROTECTION COMPOSITIONS BASED ON A SYNERGIC MIXTURE OF FILTERS AND USES L'OREAL (FR) 2002-06-27 WO claimed
EP-3709966-B1 COMPOSITIONS COMPRISING AT LEAST ONE ACRYLIC POLYMER AND AT LEAST ONE INSOLUBLE ORGANIC SCREENING AGENT OREAL (FR) 2024-12-11 EP disclosed
US-20210346249-A1 COMPOSITION COMPRISING A UV-SCREENING AGENT, AN ANIONIC CROSSLINKED HYDROPHILIC POLYMER, A SURFACTANT HAVING AN HLB LESS THAN OR EQUAL TO 5 AND A SILICONE COPOLYMER L'OREAL (FR) 2021-11-11 US disclosed
CN-107847414-B Composition comprising a UV screening agent, an anionically crosslinked hydrophilic polymer, a surfactant having an HLB less than or equal to 5, and a siloxane copolymer 欧莱雅 2021-09-10 CN disclosed
EP-3185843-B1 GEL COMPOSITION AND GEL COMPRISING A UV FILTER OREAL (FR) 2021-08-11 EP disclosed
WO-2002049597-A2 COSMETIC SOLAR PROTECTION COMPOSITIONS BASED ON A SYNERGIC MIXTURE OF FILTERS AND USES L'OREAL (FR) 2002-06-27 WO disclosed
US-4587261-A FATTENING AGENTS FOR ANIMALS EGYT GYOGYSZERVEGYESZETI GYAR (HU) 1986-05-06 US disclosed
EP-0004624-B1 CHROMANON DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS MEDICINES AND GROWTH-PROMOTING AGENTS BAYER AG (DE) 1982-02-24 EP disclosed
US-4261988-A ANTICHOLESTEROL AGENTS USED IN ANIMAL HUSBANDRY BAYER AKTIENGESELLSCHAFT (DE) 1981-04-14 US disclosed
EP-0004624-A2 Chromanon derivatives, process for their preparation, and their use as medicines and growth-promoting agents BAYER AG (DE) 1979-10-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080194882-A1 Process For Production of 2-Benzylphenol Compound CYP1B1, CYP4B1, CYP1A1 CYP1A2 17/4885EGFR 3278/4885DYRK1A 3425/4885
US-20040047820-A1 Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds SUCLG1, CUTA, DLD CYP1A2 1004/4885EGFR 3938/4885DYRK1A 1733/4885
US-20210346249-A1 COMPOSITION COMPRISING A UV-SCREENING AGENT, AN ANIONIC CROSSLINKED HYDROPHILIC POLYMER, A SURFACTANT HAVING AN HLB LESS THAN OR EQUAL TO 5 AND A SILICONE COPOLYMER ERCC5, CUTA, PLIN5 CYP1A2 3204/4885EGFR 445/4885DYRK1A 3053/4885
US-20030152532-A1 SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS HADHB, SDHA, ERCC4 CYP1A2 738/4885EGFR 2825/4885DYRK1A 2459/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.