Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.78 |
| ▸ | EGFR | P00533 | 7/20 | 0.68 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.63 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.63 |
| ▸ | CLK1 | P49759 | 1/20 | 0.63 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.62 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1524447 | 1.00 | CYP1A2 (0.78) | CYP1A2EGFRDYRK1ADYRK1BCLK1 | |
| SCHEMBL812347 | 1.00 | CYP1A2 (0.78) | CYP1A2EGFRDYRK1ADYRK1BCLK1 | |
| SCHEMBL13299359 | 0.97 | CYP1A2 (0.73) | CYP1A2EGFRDYRK1ADYRK1BCLK1 | |
| SCHEMBL624586 | 0.97 | CYP1A2 (0.73) | CYP1A2EGFRDYRK1ADYRK1BCLK1 | |
| SCHEMBL3258032 | 0.97 | CYP1A2 (0.73) | CYP1A2EGFRDYRK1ADYRK1BCLK1 | |
| SCHEMBL29506220 | 0.89 | CYP1A2 (0.71) | CYP1A2EGFRDYRK1ADYRK1BCLK1 | |
| SCHEMBL17693074 | 0.88 | CYP1A2 (1.00) | CYP1A2EGFRDYRK1ADYRK1BCLK1 | |
| SCHEMBL1524674 | 0.83 | EGFR (0.93) | EGFRXDHNFE2L2 | |
| SCHEMBL1524672 | 0.83 | EGFR (0.93) | EGFRXDHNFE2L2 | |
| SCHEMBL1524436 | 0.82 | RAB9A (0.59) | CYP1A2EGFRDYRK1ADYRK1BCLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210346249-A1 | COMPOSITION COMPRISING A UV-SCREENING AGENT, AN ANIONIC CROSSLINKED HYDROPHILIC POLYMER, A SURFACTANT HAVING AN HLB LESS THAN OR EQUAL TO 5 AND A SILICONE COPOLYMER | L'OREAL (FR) | 2021-11-11 | — | — | US | disclosed |
| EP-2872107-B1 | COSMETIC COMPOSITION CONTAINING SCREENING COMPOSITE PARTICLES | OREAL (FR) | 2021-07-21 | — | — | EP | disclosed |
| US-20200360264-A1 | COMPOSITIONS COMPRISING AT LEAST ONE ACRYLIC POLYMER AND AT LEAST ONE INSOLUBLE ORGANIC SCREENING AGENT | L'OREAL (FR) | 2020-11-19 | — | — | US | disclosed |
| US-20200030200-A1 | COMPOSITION COMPRISING A UV-SCREENING AGENT, AN ANIONIC CROSSLINKED HYDROPHILIC POLYMER, A SURFACTANT HAVING AN HLB LESS THAN OR EQUAL TO 5 AND A SILICONE COPOLYMER | L'OREAL (FR) | 2020-01-30 | — | — | US | disclosed |
| US-20170326045-A1 | COSMETIC COMPOSITION COMPRISING A SYNTHETIC PHYLLOSILICATE AND A POLYOL AND/OR A UV FILTER | L'OREAL (FR) | 2017-11-16 | — | — | US | disclosed |
| US-20170304658-A1 | GEL/GEL COMPOSITION COMPRISING A UV-SCREENING AGENT | L'OREAL (FR) | 2017-10-26 | — | — | US | disclosed |
| WO-2016198581-A1 | COMPOSITION COMPRISING A UV-SCREENING AGENT, AN ANIONIC CROSSLINKED HYDROPHILIC POLYMER, A SURFACTANT HAVING AN HLB LESS THAN OR EQUAL TO 5 AND A SILICONE COPOLYMER | L'OREAL (FR) | 2016-12-15 | — | — | WO | disclosed |
| US-20150190320-A1 | COSMETIC COMPOSITION COMPRISING COMPOSITE SUNSCREEN PARTICLES | L'OREAL (FR) | 2015-07-09 | — | — | US | disclosed |
| US-20150157539-A1 | COSMETIC COMPOSITION COMPRISING COMPOSITE PARTICLES | L'OREAL (FR) | 2015-06-11 | — | — | US | disclosed |
| WO-2014010099-A1 | COMPOSITE PIGMENT AND METHOD FOR PREPARING THE SAME | L'OREAL (FR) | 2014-01-16 | — | — | WO | disclosed |
| US-7968734-B2 | Organocatalysts and methods of use in chemical synthesis | STC.UNM (US) | 2011-06-28 | — | — | US | disclosed |
| EP-2196189-A1 | Cosmetic sunscreen compositions based on synergistic filter mixture and their use | L'OREAL (FR) | 2010-06-16 | — | — | EP | disclosed |
| US-7416721-B2 | Sunscreen compositions comprising insoluble organic UV-screening agents and hydroxyalkylurea compounds | L'OREAL (FR) | 2008-08-26 | — | — | US | disclosed |
| US-7416721-B2 | Sunscreen compositions comprising insoluble organic UV-screening agents and hydroxyalkylurea compounds | L'OREAL (FR) | 2008-08-26 | — | — | US | disclosed |
| WO-2008086928-A1 | O/W COSMETIC EMULSION COMPRISING A LIPOPHILIC UV SCREENING AGENT, A POLAR OIL AND A POLYSTYRENE-BLOCK-POLY(ACRYLIC ACID-STAT-C1-C4 ALKYL ACRYLATE) DIBLOCK COPOLYMER | L'OREAL (FR) | 2008-07-24 | — | — | WO | disclosed |
| US-20070244328-A1 | Organocatalysts and Methods of Use in Chemical Synthesis | STC.UNM (US) | 2007-10-18 | — | — | US | disclosed |
| US-20070244328-A1 | Organocatalysts and Methods of Use in Chemical Synthesis | STC.UNM (US) | 2007-10-18 | — | — | US | disclosed |
| US-20070244328-A1 | Organocatalysts and Methods of Use in Chemical Synthesis | STC.UNM (US) | 2007-10-18 | — | — | US | disclosed |
| US-7166274-B2 | Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds | L'OREAL (FR) | 2007-01-23 | — | — | US | disclosed |
| US-7166274-B2 | Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds | L'OREAL (FR) | 2007-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244328-A1 | Organocatalysts and Methods of Use in Chemical Synthesis | SCO2, CBR1, CBR3 | CYP1A2 82/4885EGFR 1024/4885DYRK1A 2487/4885 |
| US-20200360264-A1 | COMPOSITIONS COMPRISING AT LEAST ONE ACRYLIC POLYMER AND AT LEAST ONE INSOLUBLE ORGANIC SCREENING AGENT | PCNA, ERCC1, XRCC6 | CYP1A2 4136/4885EGFR 2152/4885DYRK1A 3992/4885 |
| US-20170326045-A1 | COSMETIC COMPOSITION COMPRISING A SYNTHETIC PHYLLOSILICATE AND A POLYOL AND/OR A UV FILTER | PUF60, POLR1C, DPM1 | CYP1A2 2541/4885EGFR 1899/4885DYRK1A 3654/4885 |
| US-20150157539-A1 | COSMETIC COMPOSITION COMPRISING COMPOSITE PARTICLES | MITF, RAB5IF, TYR | CYP1A2 2069/4885EGFR 2772/4885DYRK1A 4694/4885 |
| US-20200030200-A1 | COMPOSITION COMPRISING A UV-SCREENING AGENT, AN ANIONIC CROSSLINKED HYDROPHILIC POLYMER, A SURFACTANT HAVING AN HLB LESS THAN OR EQUAL TO 5 AND A SILICONE COPOLYMER | ERCC5, CUTA, PLIN5 | CYP1A2 3204/4885EGFR 445/4885DYRK1A 3053/4885 |
| US-20170304658-A1 | GEL/GEL COMPOSITION COMPRISING A UV-SCREENING AGENT | CUTA, KRT18, APOL1 | CYP1A2 1980/4885EGFR 1124/4885DYRK1A 2094/4885 |
| US-20210346249-A1 | COMPOSITION COMPRISING A UV-SCREENING AGENT, AN ANIONIC CROSSLINKED HYDROPHILIC POLYMER, A SURFACTANT HAVING AN HLB LESS THAN OR EQUAL TO 5 AND A SILICONE COPOLYMER | ERCC5, CUTA, PLIN5 | CYP1A2 3204/4885EGFR 445/4885DYRK1A 3053/4885 |
| US-20150190320-A1 | COSMETIC COMPOSITION COMPRISING COMPOSITE SUNSCREEN PARTICLES | XPA, ERCC1, ERCC4 | CYP1A2 621/4885EGFR 1676/4885DYRK1A 4610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.