Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.78 |
| ▸ | EGFR | P00533 | 7/20 | 0.68 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.63 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.63 |
| ▸ | CLK1 | P49759 | 1/20 | 0.63 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.62 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL809541 | 1.00 | CYP1A2 (0.78) | CYP1A2EGFRDYRK1ADYRK1BCLK1 | |
| SCHEMBL1524447 | 1.00 | CYP1A2 (0.78) | CYP1A2EGFRDYRK1ADYRK1BCLK1 | |
| SCHEMBL13299359 | 0.97 | CYP1A2 (0.73) | CYP1A2EGFRDYRK1ADYRK1BCLK1 | |
| SCHEMBL624586 | 0.97 | CYP1A2 (0.73) | CYP1A2EGFRDYRK1ADYRK1BCLK1 | |
| SCHEMBL3258032 | 0.97 | CYP1A2 (0.73) | CYP1A2EGFRDYRK1ADYRK1BCLK1 | |
| SCHEMBL29506220 | 0.89 | CYP1A2 (0.71) | CYP1A2EGFRDYRK1ADYRK1BCLK1 | |
| SCHEMBL17693074 | 0.88 | CYP1A2 (1.00) | CYP1A2EGFRDYRK1ADYRK1BCLK1 | |
| SCHEMBL1524674 | 0.83 | EGFR (0.93) | EGFRXDHNFE2L2 | |
| SCHEMBL1524672 | 0.83 | EGFR (0.93) | EGFRXDHNFE2L2 | |
| SCHEMBL1524436 | 0.82 | RAB9A (0.59) | CYP1A2EGFRDYRK1ADYRK1BCLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102557969-B | Cyclic ketone derivatives and applications thereof as developers and aggregation inhibitors of amyloid protein sediments and neurofibrillary tangles | USTC UNIV SCIENCE TECH CN | 2015-03-18 | — | — | CN | claimed |
| US-7166274-B2 | Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds | L'OREAL (FR) | 2007-01-23 | — | — | US | claimed |
| US-20040047820-A1 | Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds | SOCIETE L'OREAL S.A. (FR) | 2004-03-11 | — | — | US | claimed |
| EP-1370232-A2 | COSMETIC SOLAR PROTECTION COMPOSITIONS BASED ON A SYNERGIC MIXTURE OF FILTERS AND USES | L'OREAL (FR) | 2003-12-17 | — | — | EP | claimed |
| US-6627180-B2 | Particles having protection factor UV-APPD and an amino substituted 2-hydroxybenzophenone | SOCIETE L'OREAL S.A. (FR) | 2003-09-30 | — | — | US | claimed |
| US-20030152532-A1 | SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS | SOCIETE L'OREAL S.A. (FR) | 2003-08-14 | — | — | US | claimed |
| EP-1317918-A1 | Cosmetic sunscreen compositions based on synergistic filter mixture and their use | L'OREAL (FR) | 2003-06-11 | — | — | EP | claimed |
| WO-2002056858-A1 | SOLAR PROTECTION COMPOSITIONS | L'OREAL (FR) | 2002-07-25 | — | — | WO | claimed |
| WO-2002049597-A2 | COSMETIC SOLAR PROTECTION COMPOSITIONS BASED ON A SYNERGIC MIXTURE OF FILTERS AND USES | L'OREAL (FR) | 2002-06-27 | — | — | WO | claimed |
| EP-3709966-B1 | COMPOSITIONS COMPRISING AT LEAST ONE ACRYLIC POLYMER AND AT LEAST ONE INSOLUBLE ORGANIC SCREENING AGENT | OREAL (FR) | 2024-12-11 | — | — | EP | disclosed |
| US-20210346249-A1 | COMPOSITION COMPRISING A UV-SCREENING AGENT, AN ANIONIC CROSSLINKED HYDROPHILIC POLYMER, A SURFACTANT HAVING AN HLB LESS THAN OR EQUAL TO 5 AND A SILICONE COPOLYMER | L'OREAL (FR) | 2021-11-11 | — | — | US | disclosed |
| CN-107847414-B | Composition comprising a UV screening agent, an anionically crosslinked hydrophilic polymer, a surfactant having an HLB less than or equal to 5, and a siloxane copolymer | 欧莱雅 | 2021-09-10 | — | — | CN | disclosed |
| EP-3185843-B1 | GEL COMPOSITION AND GEL COMPRISING A UV FILTER | OREAL (FR) | 2021-08-11 | — | — | EP | disclosed |
| EP-2872107-B1 | COSMETIC COMPOSITION CONTAINING SCREENING COMPOSITE PARTICLES | OREAL (FR) | 2021-07-21 | — | — | EP | disclosed |
| EP-1302197-A1 | Use of amphiphilic copolymers to stabilise dispersions of non-soluble organic compounds filtering UV light | L'OREAL (FR) | 2003-04-16 | — | — | EP | disclosed |
| US-20030053966-A1 | Insoluble organic UV screening agents of aryl vinylene ketone type, and cosmetic use thereof | L'OREAL (FR) | 2003-03-20 | — | — | US | disclosed |
| EP-1281391-A1 | Organic insoluble UV filters of the aryl vinylene ketone type and their use in cosmetics | L'OREAL (FR) | 2003-02-05 | — | — | EP | disclosed |
| WO-2002049597-A2 | COSMETIC SOLAR PROTECTION COMPOSITIONS BASED ON A SYNERGIC MIXTURE OF FILTERS AND USES | L'OREAL (FR) | 2002-06-27 | — | — | WO | disclosed |
| US-4035395-A | Process for the preparation of ketones | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-12 | — | — | US | disclosed |
| US-4014889-A | Process for preparing ketones | BAYER AKTIENGESELLSCHAFT (DT) | 1977-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040047820-A1 | Synergistically high SPF photoprotective UV-screening compositions comprising insoluble organic sunscreen particles/diarylbutadiene compounds | SUCLG1, CUTA, DLD | CYP1A2 1004/4885EGFR 3938/4885DYRK1A 1733/4885 |
| US-20030053966-A1 | Insoluble organic UV screening agents of aryl vinylene ketone type, and cosmetic use thereof | PRKDC, AHR, TYR | CYP1A2 281/4885EGFR 588/4885DYRK1A 2484/4885 |
| US-20210346249-A1 | COMPOSITION COMPRISING A UV-SCREENING AGENT, AN ANIONIC CROSSLINKED HYDROPHILIC POLYMER, A SURFACTANT HAVING AN HLB LESS THAN OR EQUAL TO 5 AND A SILICONE COPOLYMER | ERCC5, CUTA, PLIN5 | CYP1A2 3204/4885EGFR 445/4885DYRK1A 3053/4885 |
| US-20030152532-A1 | SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS | HADHB, SDHA, ERCC4 | CYP1A2 738/4885EGFR 2825/4885DYRK1A 2459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.