SCHEMBL6246191

SCHEMBL6246191

COc1cccc(Oc2cc(-n3c(=O)cc(C(F)(F)F)n(C)c3=O)c(F)cc2Br)c1

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.37
MAPT P10636 2/20 0.37
NPSR1 Q6W5P4 1/20 0.37
BCAT1 P54687 9/20 0.37
BCAT2 O15382 7/20 0.37
JAK2 O60674 3/20 0.37
BTK Q06187 3/20 0.37
NPC1 O15118 1/20 0.36
ALDH1A1 P00352 1/20 0.36
GAA P10253 1/20 0.36
RAB9A P51151 1/20 0.36
KDM4E B2RXH2 2/20 0.34
POLB P06746 1/20 0.34
LMNA P02545 1/20 0.34
CRHR1 P34998 1/20 0.33
TRIM24 O15164 1/20 0.32
BRD1 O95696 1/20 0.32
BRPF1 P55201 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6243698 0.88 L3MBTL1 (0.47) L3MBTL1MAPTNPSR1BCAT1BCAT2
SCHEMBL25095599 0.86 BCAT1 (0.42) BCAT1BCAT2JAK2BTKCRHR1
SCHEMBL6248581 0.86 BCAT1 (0.54) BCAT1BCAT2
SCHEMBL7881673 0.85 CRHR1 (0.34) L3MBTL1BCAT1BCAT2JAK2BTK
SCHEMBL6243873 0.85 SMN1; SMN2 (0.36) L3MBTL1MAPTNPSR1BCAT1BCAT2
SCHEMBL25095853 0.81 BCAT1 (0.41) BCAT1BCAT2JAK2BTKALDH1A1
SCHEMBL8914465 0.79 BCAT1 (0.37) BCAT1BCAT2
SCHEMBL29005621 0.79 BCAT1 (0.39) BCAT1BCAT2
SCHEMBL9115133 0.79 SMN1; SMN2 (0.38) MAPTBCAT1BCAT2NPC1ALDH1A1
SCHEMBL7887149 0.79 BCAT1 (0.31) BCAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1106607-B1 Uracil compounds and their use SUMITOMO CHEMICAL CO (JP) 2005-07-27 EP disclosed
US-6667413-B2 Aniline derivatives; herbicides; nonphytotoxic SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-12-23 US disclosed
US-20030130124-A1 Herbicides SUMITOMO CHEMICAL COMPANY, LIMITED 2003-07-10 US disclosed
US-6451740-B2 HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-09-17 US disclosed
US-20020013466-A1 Uracil compounds and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-01-31 US disclosed
EP-1106607-A2 Uracil compounds and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-06-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030130124-A1 Herbicides CBR3, CBR1, MT-CO1 L3MBTL1 295/4885MAPT 4776/4885NPSR1 3876/4885
US-20020013466-A1 Uracil compounds and use thereof UNG, MRM1, OGG1 L3MBTL1 117/4885MAPT 4788/4885NPSR1 4141/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.