Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 11/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | HPD | P32754 | 2/20 | 0.40 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2986176 | 0.88 | DDB1 (0.54) | CTSSHSD11B1DDB1CRBNPARP1 | |
| Hydrochloric Acid SCHEMBL2858713 | 0.87 | DDB1 (0.52) | CTSSHSD11B1DDB1CRBNPARP1 | |
| Trifluoroacetic Acid SCHEMBL3765036 | 0.84 | PRKDC (0.42) | CTSSPARP1PARP2CRHR1 | |
| Trifluoroacetic Acid SCHEMBL6245311 | 0.81 | CRHR1 (0.46) | OPRM1OPRL1CRHR1 | |
| Trifluoroacetic Acid SCHEMBL6246599 | 0.81 | C5AR1 (0.54) | PARP1PARP2CYP3A4 | |
| SCHEMBL2636509 | 0.80 | DDB1 (0.51) | CTSSHSD11B1DDB1CRBNPARP1 | |
| SCHEMBL2636510 | 0.80 | DDB1 (0.51) | CTSSHSD11B1DDB1CRBNPARP1 | |
| Trifluoroacetic Acid SCHEMBL4446739 | 0.79 | HPD (0.41) | HSD11B1OPRM1HPD | |
| Trifluoroacetic Acid SCHEMBL6580575 | 0.78 | OPRL1 (0.42) | OPRM1OPRL1 | |
| SCHEMBL23937829 | 0.78 | DDB1 (0.56) | CTSSHSD11B1DDB1CRBNCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1256575-B1 | PHENOXYALKYLAMINE DERIVATIVES USEFUL AS OPIOID DELTA RECEPTOR AGONISTS | MEIJI SEIKA KAISHA (JP) | 2005-08-17 | — | — | EP | disclosed |
| US-6916822-B2 | Phenoxyalkylamine derivatives useful as opioid δ receptor agonists | MEIJI SEIKA KAISHA, LTD. (JP) | 2005-07-12 | — | — | US | disclosed |
| US-20050148583-A1 | Phenoxyalkylamine derivatives useful as opioid delta receptor ligands | MEIJI SEIKA KAISHA, LTD. (JP) | 2005-07-07 | — | — | US | disclosed |
| US-20030171370-A1 | Phenoxyalkylamine derivatives useful as opioid receptor agonists | MEIJI SEIKA KAISHA, LTD. (JP) | 2003-09-11 | — | — | US | disclosed |
| EP-1256575-A1 | PHENOXYALKYLAMINE DERIVATIVES USEFUL AS OPIOID DELTA RECEPTOR AGONISTS | MEIJI SEIKA KAISHA LTD. (JP) | 2002-11-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030171370-A1 | Phenoxyalkylamine derivatives useful as opioid receptor agonists | OPRM1, OPRK1, OPRD1 | CTSS 2849/4885HSD11B1 2154/4885DDB1 4719/4885 |
| US-20050148583-A1 | Phenoxyalkylamine derivatives useful as opioid delta receptor ligands | OPRD1, OPRM1, OPRK1 | CTSS 3202/4885HSD11B1 1115/4885DDB1 4386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.