Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.46 |
| ▸ | LMNA | P02545 | 8/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 10/20 | 0.46 |
| ▸ | NPC1 | O15118 | 10/20 | 0.45 |
| ▸ | RAB9A | P51151 | 10/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.41 |
| ▸ | RELA | Q04206 | 3/20 | 0.41 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL624357 | 0.78 | RAB9A (0.51) | MAPTLMNAPOLBNPC1RAB9A | |
| SCHEMBL625756 | 0.74 | CHRM4 (0.52) | MAPTLMNAPOLBTP53NPC1 | |
| SCHEMBL10083553 | 0.73 | KDM4E (0.51) | POLBMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL627181 | 0.72 | ROCK2 (0.54) | NPC1RAB9ATMIGD3ADORA1MAPK1 | |
| SCHEMBL623932 | 0.72 | RAB9A (0.59) | MAPTPOLBNPC1RAB9AKMT2A | |
| SCHEMBL623623 | 0.70 | KDR (0.53) | MAPTPOLBTP53NPC1RAB9A | |
| SCHEMBL625959 | 0.69 | HDAC6 (0.46) | LMNAPOLBTP53NPC1RAB9A | |
| SCHEMBL10084313 | 0.66 | MEN1 (0.34) | MAPTPOLBRAB9AMEN1KMT2A | |
| SCHEMBL623924 | 0.66 | ABL1 (0.56) | MAPTALDH1A1HTTMAPK1 | |
| SCHEMBL624210 | 0.65 | MAPK8 (0.39) | MAPTLMNAPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020080-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY II | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-16 | — | — | WO | disclosed |