Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | PLD2 | O14939 | 1/20 | 0.35 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6210874 | 0.91 | ALDH1A1 (0.40) | LMNACTSKHPGDHTTCHRM4 | |
| SCHEMBL6209043 | 0.91 | LMNA (0.41) | LMNACTSKPOLBSMN1; SMN2 | |
| SCHEMBL6211167 | 0.89 | CTSK (0.39) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL6210327 | 0.89 | GAA (0.45) | LMNAHPGDCHRM4POLBNPSR1 | |
| SCHEMBL6212088 | 0.89 | SLC6A5 (0.40) | LMNACTSKHTTCHRM4NAMPT | |
| SCHEMBL6209727 | 0.88 | CHRM4 (0.42) | LMNACTSKHPGDHTTCHRM4 | |
| SCHEMBL6212884 | 0.88 | LMNA (0.37) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL6210258 | 0.87 | POLB (0.42) | LMNACTSKHPGDCHRM4POLB | |
| SCHEMBL6211236 | 0.87 | PTAFR (0.40) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL6209614 | 0.87 | ROCK2 (0.41) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | claimed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | claimed |