Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26310589 | 0.79 | CTSK (0.47) | CTSKSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL6654292 | 0.79 | FAAH (0.42) | CTSKSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL6654077 | 0.79 | PLA2G10 (0.46) | CTSKSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL15564679 | 0.77 | ALDH1A1 (0.43) | CTSKSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL7447301 | 0.77 | CTSK (0.44) | CTSKSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL6656147 | 0.76 | FAAH (0.41) | CTSKSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL24095786 | 0.74 | EPHX1 (0.47) | — | |
| SCHEMBL2052808 | 0.73 | SMN1; SMN2 (0.56) | CTSKSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL7454120 | 0.73 | SMN1; SMN2 (0.56) | CTSKSMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL7742011 | 0.73 | CTSL (0.55) | CTSKTDP1L3MBTL1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0958287-A1 | SULFAMIDE-METALLOPROTEASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 1999-11-24 | — | — | EP | disclosed |
| WO-1998032748-A1 | SULFAMIDE-METALLOPROTEASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 1998-07-30 | — | — | WO | disclosed |