Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.57 |
| ▸ | RAB9A | P51151 | 8/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.49 |
| ▸ | RELA | Q04206 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL625028 | 0.89 | DYRK1A (0.52) | NPC1RAB9AL3MBTL1PKMPAX8 | |
| SCHEMBL625958 | 0.84 | SMN1; SMN2 (0.60) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL625106 | 0.81 | RAB9A (0.48) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL625180 | 0.80 | ADORA3 (0.53) | L3MBTL1PKMPAX8MAPTMEN1 | |
| SCHEMBL624218 | 0.80 | KCNMA1 (0.53) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL10083535 | 0.78 | DDX3X (0.49) | MAPTMEN1KMT2AMCHR1 | |
| SCHEMBL627332 | 0.78 | MAPT (0.49) | NPC1RAB9AL3MBTL1MAPTMEN1 | |
| SCHEMBL10083543 | 0.78 | MCHR1 (0.47) | PKMGAAMCHR1 | |
| SCHEMBL10182254 | 0.76 | NPC1 (0.48) | NPC1RAB9APKMPAX8KLF5 | |
| SCHEMBL623943 | 0.76 | MEN1 (0.51) | NPC1RAB9AMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020080-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY II | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-16 | — | — | WO | disclosed |