SCHEMBL6273699

SCHEMBL6273699

COc1ccc(C(SC[C@H](NC(=O)OCC2c3ccccc3-c3ccccc32)C(=O)O)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MDM2 Q00987 4/20 0.54
KIF11 P52732 5/20 0.53
MDM4 O15151 3/20 0.53
TP53 P04637 3/20 0.53
SLC17A5 Q9NRA2 1/20 0.46
CASP3 P42574 1/20 0.45
TLR2 O60603 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21639223 1.00 MDM2 (0.54) MDM2KIF11MDM4TP53SLC17A5
SCHEMBL29400885 1.00 MDM2 (0.54) MDM2KIF11MDM4TP53SLC17A5
SCHEMBL29460482 1.00 MDM2 (0.54) MDM2KIF11MDM4TP53SLC17A5
SCHEMBL29395463 0.92 MDM4 (0.55) MDM2MDM4TP53SLC17A5CASP3
SCHEMBL29560536 0.92 MDM4 (0.55) MDM2MDM4TP53SLC17A5CASP3
SCHEMBL1738641 0.92 MDM4 (0.55) MDM2MDM4TP53SLC17A5CASP3
SCHEMBL5998507 0.92 MDM4 (0.55) MDM2MDM4TP53SLC17A5CASP3
SCHEMBL3436122 0.92 MDM4 (0.55) MDM2MDM4TP53SLC17A5CASP3
SCHEMBL29503847 0.92 MDM4 (0.55) MDM2MDM4TP53SLC17A5CASP3
SCHEMBL12127262 0.92 KIF11 (0.51) MDM2KIF11MDM4TP53CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120137003-A Method for chemically synthesizing glycosylated insulin 中国医学科学院药物研究所 2025-06-13 CN claimed
CN-113801196-B Preparation method of procalcitonin 深圳翰宇药业股份有限公司 2024-07-23 CN claimed
CN-118290538-A GABA with analgesic activityAReceptor targeting peptide DZ2 and synthesis method and application thereof 河北医科大学 2024-07-05 CN claimed
CN-113929763-B Method for preparing semenopeptide by using soluble label as carrier 申联生物医药(上海)股份有限公司 2024-01-30 CN claimed
CN-115894630-A Preparation method of linaclotide 四川轻化工大学 2023-04-04 CN claimed
CN-114044813-B Preparation and purification method of procatide 浙江湃肽生物有限公司南京分公司 2022-04-15 CN claimed
CN-113956333-B Synthesis and purification method of linaclotide 浙江湃肽生物有限公司南京分公司 2022-03-29 CN claimed
CN-110609078-B Method for detecting protein phosphorylation and acetylglucosamine saccharification correlation effect 南京谱利健生物技术有限公司 2022-03-11 CN claimed
CN-114133455-A Synthesis method of desmopressin acetate dimer impurity 深圳翰宇药业股份有限公司 2022-03-04 CN claimed
CN-114044813-A Preparation and purification method of procatide 浙江湃肽生物有限公司南京分公司 2022-02-15 CN claimed
EP-4745151-A1 FIBROBLAST ACTIVATION PROTEIN LIGAND AND USE THEREOF Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) 2026-05-20 EP disclosed
US-20260116922-A1 HIGHLY STABLE OXYTOCIN DERIVATIVES UNIVERSITAET WIEN (AT) 2026-04-30 US disclosed
US-20260115268-A1 Heat-Stable Enterotoxins Mutants as Antidiarrheal Vaccine Antigens VESTLANDETS INNOVASJONSSELSKAP AS (NO) 2026-04-30 US disclosed
US-12577274-B2 Manufacture of glucagon peptides BACHEM HOLDING AG (CH) 2026-03-17 US disclosed
US-12527853-B2 Heat-stable enterotoxins mutants as antidiarrheal vaccine antigens VESTLANDETS INNOVASJONSSELSKAP AS (VIS) (NO) 2026-01-20 US disclosed
US-7964729-B2 Sox-based kinase sensor MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2011-06-21 US disclosed
WO-2008082715-A2 SOX-BASED KINASE SENSOR MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2008-07-10 WO disclosed
US-20080050761-A1 Sox-based kinase sensor MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2008-02-28 US disclosed
US-20080050761-A1 Sox-based kinase sensor MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2008-02-28 US disclosed
WO-2005108353-A2 COMPOUNDS FOR TREATING NEUROLOGIC DISEASES, OTOLOGIC DISEASES, OR OPHTHALMOLOGIC DISEASES AND METHODS OF USE THEREOF CEPTOR CORPORATION (US) 2005-11-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260115268-A1 Heat-Stable Enterotoxins Mutants as Antidiarrheal Vaccine Antigens SCN8A, SCN9A, VIP MDM2 4474/4885KIF11 2147/4885MDM4 4004/4885
US-20080050761-A1 Sox-based kinase sensor SOX18, HIPK1, HIPK3 MDM2 1622/4885KIF11 3044/4885MDM4 1262/4885
US-12577274-B2 Manufacture of glucagon peptides IAPP, GLP1R, GCG MDM2 4043/4885KIF11 4019/4885MDM4 4113/4885
US-12527853-B2 Heat-stable enterotoxins mutants as antidiarrheal vaccine antigens VIP, MLEC, SEC16A MDM2 3421/4885KIF11 2066/4885MDM4 2800/4885
US-20260116922-A1 HIGHLY STABLE OXYTOCIN DERIVATIVES OXTR, CRH, TRHR MDM2 3967/4885KIF11 2924/4885MDM4 4514/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.