Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 7/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 6/20 | 0.45 |
| ▸ | CES2 | O00748 | 4/20 | 0.45 |
| ▸ | FAAH | O00519 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7203595 | 0.93 | CES2 (0.46) | FABP3CA1CES1CES2FAAH | |
| SCHEMBL7890037 | 0.91 | CES2 (0.44) | FABP3CA1CES1CES2 | |
| SCHEMBL76018 | 0.91 | CES2 (0.44) | FABP3CA1CES1CES2 | |
| SCHEMBL4879952 | 0.91 | CES2 (0.44) | FABP3CA1CES1CES2 | |
| SCHEMBL9893310 | 0.91 | CES2 (0.44) | FABP3CA1CES1CES2 | |
| SCHEMBL10639504 | 0.91 | CES2 (0.44) | FABP3CA1CES1CES2 | |
| Zinc Ion SCHEMBL5681976 | 0.89 | FABP3 (0.55) | FABP3CA1CES1CES2 | |
| SCHEMBL29052286 | 0.89 | CA1 (0.45) | CA1CES1CES2 | |
| Dodecanoate SCHEMBL5710745 | 0.88 | FABP3 (0.53) | FABP3CA1CES1CES2 | |
| Dodecanoate SCHEMBL28628262 | 0.88 | FABP3 (0.53) | FABP3CA1CES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200199473-A1 | GREASE COMPOSITIONS HAVING IMPROVED PERFORMANCE | EXXONMOBIL RES & ENG CO (US) | 2020-06-25 | — | — | US | disclosed |
| WO-2020131441-A1 | GREASE COMPOSITIONS HAVING IMPROVED PERFORMANCE | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2020-06-25 | — | — | WO | disclosed |
| EP-2231839-B1 | USE IN GREASE FORMULATIONS | SHELL INT RESEARCH (NL) | 2017-11-15 | — | — | EP | disclosed |
| US-9556396-B2 | Grease formulations | SHELL OIL COMPANY (US) | 2017-01-31 | — | — | US | disclosed |
| US-9126924-B2 | Chemical composition | THE CHARLES STARK DRAPER LABORATORY, INC. (US) | 2015-09-08 | — | — | US | disclosed |
| US-9062272-B2 | Lubricant composition and methods of using same | THE CHARLES STARK DRAPER LABORATORY, INC. (US) | 2015-06-23 | — | — | US | disclosed |
| EP-2859071-A2 | CHEMICAL COMPOSITIONS AND METHODS OF USING SAME | The Charles Stark Draper Laboratory, Inc. (US) | 2015-04-15 | — | — | EP | disclosed |
| US-20130331589-A1 | CHEMICAL COMPOSITION | THE CHARLES STARK DRAPER LABORATORY, INC. (US) | 2013-12-12 | — | — | US | disclosed |
| US-20130327594-A1 | LUBRICANT COMPOSITION AND METHODS OF USING SAME | THE CHARLES STARK DRAPER LABORATORY, INC. (US) | 2013-12-12 | — | — | US | disclosed |
| WO-2013185006-A2 | CHEMICAL COMPOSITIONS AND METHODS OF USING SAME | THE CHARLES STARK DRAPER LABORATORY, INC. (US) | 2013-12-12 | — | — | WO | disclosed |
| US-4530770-A | Oxidation resistance | MOBIL OIL CORPORATION (US) | 1985-07-23 | — | — | US | disclosed |
| US-4529528-A | Reacting an alkoxylated amine and a phosphite | MOBIL OIL CORPORATION (US) | 1985-07-16 | — | — | US | disclosed |
| EP-0141485-A1 | Lubricant composition | MOBIL OIL CORPORATION (US) | 1985-05-15 | — | — | EP | disclosed |
| US-4507216-A | ANTIFRICTION, ANTICORROSION, FUEL CONSUMPTION REDUCING AGENT | MOBIL OIL CORPORATION (US) | 1985-03-26 | — | — | US | disclosed |
| US-4492640-A | Trihydroxyhydrocarbyl sulfides and lubricants containing same | MOBIL OIL CORPORATION (US) | 1985-01-08 | — | — | US | disclosed |
| US-4486322-A | FRICTION AND OXIDATION RESISTANCE | MOBIL OIL CORPORATION (US) | 1984-12-04 | — | — | US | disclosed |
| US-4474670-A | OIL ADDITIVES | MOBIL OIL CORPORATION (US) | 1984-10-02 | — | — | US | disclosed |
| US-4465605-A | Borated polyhydroxyalkyl sulfides and lubricants containing same | MOBIL OIL CORPORATION (US) | 1984-08-14 | — | — | US | disclosed |
| US-4456539-A | ANTIOXIDANTS | MOBIL OIL CORPORATION (US) | 1984-06-26 | — | — | US | disclosed |
| US-4200542-A | Grease composition | MOBIL OIL CORPORATION (US) | 1980-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130331589-A1 | CHEMICAL COMPOSITION | VCL, SDC2, MUC1 | FABP3 1490/4885CA1 165/4885CES1 2408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.