Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.43 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.40 |
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 4/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.40 |
| ▸ | FABP3 | P05413 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL76018 | 1.00 | CES2 (0.44) | CES2CA1GPR84CES1CA2 | |
| SCHEMBL9893310 | 1.00 | CES2 (0.44) | CES2CA1GPR84CES1CA2 | |
| SCHEMBL7890037 | 1.00 | CES2 (0.44) | CES2CA1GPR84CES1CA2 | |
| SCHEMBL10639504 | 1.00 | CES2 (0.44) | CES2CA1GPR84CES1CA2 | |
| SCHEMBL29052286 | 0.98 | CA1 (0.45) | CES2CA1GPR84CES1CA2 | |
| SCHEMBL7203595 | 0.98 | CES2 (0.46) | CES2CA1CES1FABP3EPHX1 | |
| SCHEMBL7157352 | 0.93 | CES2 (0.42) | CES2CA1GPR84CES1CA2 | |
| SCHEMBL629311 | 0.91 | FABP3 (0.51) | CES2CA1CES1FABP3 | |
| SCHEMBL7527790 | 0.89 | CA1 (0.41) | CES2CA1GPR84CA2 | |
| SCHEMBL11781930 | 0.88 | CES2 (0.46) | CES2CA1CES1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080166663-A1 | Processing method of light sensitive planographic printing plate material | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2008-07-10 | — | — | US | disclosed |
| US-20080102406-A1 | LIGHT SENSITIVE PLANOGRAPHIC PRINTING PLATE MATERIAL AND MANUFACTURING PROCESS OF PRINTING PLATE EMPLOYING THE SAME | KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) | 2008-05-01 | — | — | US | disclosed |
| US-7186497-B2 | Process of exposing the printing plate, processing with a developer solution using an automatic processor with a developing section and a washing section, andwashing the plate with water; the washing water forms the developer solution | KONICA MINOLTA HOLDINGS, INC. (JP) | 2007-03-06 | — | — | US | disclosed |
| US-20050250058-A1 | Developer composition for lithographic printing plate | KONICA MINOLTA HOLDINGS INC. | 2005-11-10 | — | — | US | disclosed |
| EP-1434102-A1 | Developer composition for lithographic printing plate | KONICA MINOLTA HOLDINGS, INC. (JP) | 2004-06-30 | — | — | EP | disclosed |
| US-6756183-B2 | IMAGEWISE EXPOSING PRESENSITIZED PLATE COMPRISING GRAINED AND ANODIZED SUBSTRATE WITH PHOTOPOLYMERIZABLE LIGHT-SENSITIVE LAYER CONTAINING ACRYLIC ACID-ITACONIC ACID COPOLYMER AND TITANOCENE PHOTOINITIATOR, THEN DEVELOPING | FUJI PHOTO FILM CO., LTD. (JP) | 2004-06-29 | — | — | US | disclosed |
| EP-1288722-A2 | Method for preparing lithographic printing plate | FUJI PHOTO FILM CO., LTD. (JP) | 2003-03-05 | — | — | EP | disclosed |
| US-5994031-A | DEVELOPMENT; WASHING | KONICA CORPORATION (JP) | 1999-11-30 | — | — | US | disclosed |