Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.32 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.32 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.32 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6273804 | 0.82 | ESR1 (0.37) | ESR1ESR2ATMNPC1RAB9A | |
| SCHEMBL686819 | 0.82 | ATM (0.36) | ESR1ESR2ATMNPC1RAB9A | |
| SCHEMBL2102291 | 0.75 | ESR1 (0.43) | ESR1ESR2ATMNR1H2NR1H3 | |
| SCHEMBL11540362 | 0.75 | ATM (0.38) | ESR1ESR2ATMNPC1RAB9A | |
| SCHEMBL2100216 | 0.71 | ESR1 (0.40) | ESR1ESR2NPC1RAB9AMAPT | |
| SCHEMBL1314801 | 0.70 | ESR1 (0.38) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL22283334 | 0.70 | ESR1 (0.39) | ESR1ESR2ATMALDH1A1CYP3A4 | |
| SCHEMBL17273048 | 0.69 | ATM (0.32) | ESR1ESR2ATMNPC1RAB9A | |
| SCHEMBL197544 | 0.68 | ESR1 (0.44) | ESR1ESR2NPC1RAB9ANR1H2 | |
| SCHEMBL68909 | 0.68 | ESR1 (0.44) | ESR1ESR2NPC1RAB9ANR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12221509-B2 | Tetraarylborate compound, catalyst composition comprising same, and method for preparing ethylene homopolymers or copolymers of ethylene and a-olefin by using same | SABIC SK NEXLENE COMPANY PTE. LTD. (SG) | 2025-02-11 | — | — | US | disclosed |
| EP-3689884-B1 | NOVEL INDENE-BASED TRANSITION METAL COMPOUND, TRANSITION METAL CATALYST COMPOSITION COMPRISING SAME, AND METHOD FOR PREPARING ETHYLENE HOMOPOLYMER OR COPOLYMER OF ETHYLENE AND ALPHA-OLEFIN BY USING SAME | SABIC SK NEXLENE COMPANY PTE LTD (SG) | 2024-07-10 | — | — | EP | disclosed |
| EP-3689884-B1 | NOVEL INDENE-BASED TRANSITION METAL COMPOUND, TRANSITION METAL CATALYST COMPOSITION COMPRISING SAME, AND METHOD FOR PREPARING ETHYLENE HOMOPOLYMER OR COPOLYMER OF ETHYLENE AND ALPHA-OLEFIN BY USING SAME | SABIC SK NEXLENE COMPANY PTE LTD (SG) | 2024-07-10 | — | — | EP | disclosed |
| EP-3904360-B1 | NOVEL TETRAARYLBORATE COMPOUND, CATALYST COMPOSITION COMPRISING SAME, AND METHOD FOR PREPARING ETHYLENE HOMOPOLYMERS OR COPOLYMERS OF ETHYLENE AND ALPHA-OLEFIN BY USING SAME | SABIC SK NEXLENE COMPANY PTE LTD (SG) | 2024-07-03 | — | — | EP | disclosed |
| CN-113677686-B | Novel tetraarylborate compounds, catalyst compositions comprising the same, and process for preparing ethylene homopolymers or copolymers of ethylene and alpha-olefins by using the same | 沙特基础工业爱思开NEXLENE私人有限公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-111148748-B | Novel indene-based transition metal compound, transition metal catalyst composition comprising the same, and method for preparing ethylene homopolymer or copolymer of ethylene and alpha-olefin by using the same | 沙特基础工业爱思开NEXLENE私人有限公司 | 2023-05-16 | — | — | CN | disclosed |
| US-20220089790-A1 | Tetraarylborate Compound, Catalyst Composition Comprising Same, and Method for Preparing Ethylene Homopolymers or Copolymers of Ethylene and a-Olefin by Using Same | SABIC SK NEXLENE COMPANY PTE. LTD. (SG) | 2022-03-24 | — | — | US | disclosed |
| CN-113677686-A | Novel tetraarylborate compound, catalyst composition comprising the same, and method for preparing ethylene homopolymer or copolymer of ethylene and alpha-olefin by using the same | 沙特基础工业爱思开NEXLENE私人有限公司 | 2021-11-19 | — | — | CN | disclosed |
| EP-3904360-A1 | NOVEL TETRAARYLBORATE COMPOUND, CATALYST COMPOSITION COMPRISING SAME, AND METHOD FOR PREPARING ETHYLENE HOMOPOLYMERS OR COPOLYMERS OF ETHYLENE AND ALPHA-OLEFIN BY USING SAME | SABIC SK Nexlene Company Pte. Ltd. (SG) | 2021-11-03 | — | — | EP | disclosed |
| US-10919992-B2 | Indene-based transition metal compound, transition metal catalyst composition comprising same, and method for preparing ethylene homopolymer or copolymer of ethylene and alpha-olefin by using same | SABIC SK NEXLENE COMPANY PTE. LTD. (SG) | 2021-02-16 | — | — | US | disclosed |
| EP-1177198-B1 | BIS(N,N-DIHYDROCARBYLAMINO)- SUBSTITUTED CYCLOPENTADIENES AND METAL COMPLEXES THEREOF | DOW GLOBAL TECHNOLOGIES INC (US) | 2002-11-20 | — | — | EP | disclosed |
| EP-1178997-A1 | DI-AND TRI-HETEROATOM SUBSTITUTED INDENYL METAL COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 2002-02-13 | — | — | EP | disclosed |
| EP-1178996-A1 | METAL COMPLEXES CONTAINING BRIDGING HETEROATOM FOR OLEFIN-POLYMERIZATION-PROCESS | THE DOW CHEMICAL COMPANY (US) | 2002-02-13 | — | — | EP | disclosed |
| EP-1177198-A1 | BIS(N,N-DIHYDROCARBYLAMINO)- SUBSTITUTED CYCLOPENTADIENES AND METAL COMPLEXES THEREOF | THE DOW CHEMICAL COMPANY (US) | 2002-02-06 | — | — | EP | disclosed |
| US-6268444-B1 | TITANIUM, ZIRCONIUM OR HAFNIUM COMPOUNDS FOR POLYMERIZATION | DOW CHEMICAL COMPANY | 2001-07-31 | — | — | US | disclosed |
| WO-2000069871-A1 | DI- AND TRI-HETEROATOM SUBSTITUTED INDENYL METAL COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 2000-11-23 | — | — | WO | disclosed |
| WO-2000069870-A1 | METAL COMPLEXES CONTAINING BRIDGING HETEROATOM FOR OLEFIN-POLYMERIZATION-PROCESS | THE DOW CHEMICAL COMPANY (US) | 2000-11-23 | — | — | WO | disclosed |
| WO-2000066596-A1 | BIS(N,N-DIHYDROCARBYLAMINO)- SUBSTITUTED CYCLOPENTADIENES AND METAL COMPLEXES THEREOF | THE DOW CHEMICAL COMPANY (US) | 2000-11-09 | — | — | WO | disclosed |
| EP-0923589-A1 | 3-HETEROATOM SUBSTITUTED CYCLOPENTADIENYL-CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS | THE DOW CHEMICAL COMPANY (US) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998006727-A1 | 3-HETEROATOM SUBSTITUTED CYCLOPENTADIENYL-CONTAINING METAL COMPLEXES AND OLEFIN POLYMERIZATION PROCESS | THE DOW CHEMICAL COMPANY (US) | 1998-02-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220089790-A1 | Tetraarylborate Compound, Catalyst Composition Comprising Same, and Method for Preparing Ethylene Homopolymers or Copolymers of Ethylene and a-Olefin by Using Same | ETFB, NOTUM, ATIC | ESR1 144/4885ESR2 660/4885ATM 616/4885 |
| US-12221509-B2 | Tetraarylborate compound, catalyst composition comprising same, and method for preparing ethylene homopolymers or copolymers of ethylene and a-olefin by using same | ETFB, NOTUM, ATIC | ESR1 169/4885ESR2 825/4885ATM 632/4885 |
| US-10919992-B2 | Indene-based transition metal compound, transition metal catalyst composition comprising same, and method for preparing ethylene homopolymer or copolymer of ethylene and alpha-olefin by using same | ETFB, EMC2, ICMT | ESR1 28/4885ESR2 162/4885ATM 2298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.