Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | PSMB11 | A5LHX3 | 5/20 | 0.35 |
| ▸ | PSMA7 | O14818 | 5/20 | 0.35 |
| ▸ | PSMB1 | P20618 | 5/20 | 0.35 |
| ▸ | PSMA1 | P25786 | 5/20 | 0.35 |
| ▸ | PSMA2 | P25787 | 5/20 | 0.35 |
| ▸ | PSMA3 | P25788 | 5/20 | 0.35 |
| ▸ | PSMA4 | P25789 | 5/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 5/20 | 0.35 |
| ▸ | PSMB9 | P28065 | 5/20 | 0.35 |
| ▸ | PSMA5 | P28066 | 5/20 | 0.35 |
| ▸ | PSMB4 | P28070 | 5/20 | 0.35 |
| ▸ | PSMB6 | P28072 | 5/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10835660 | 0.92 | L3MBTL1 (0.41) | ALDH1A1NPSR1L3MBTL1USP2ALOX15 | |
| SCHEMBL5859549 | 0.82 | ALDH1A1 (0.44) | ALDH1A1NPSR1L3MBTL1USP2ALOX15 | |
| SCHEMBL10337081 | 0.79 | PSMB11 (0.34) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL28649391 | 0.77 | RAB9A (0.33) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL10394014 | 0.76 | ALDH1A1 (0.38) | ALDH1A1NPSR1L3MBTL1USP2ALOX15 | |
| SCHEMBL10394018 | 0.76 | ALDH1A1 (0.38) | ALDH1A1NPSR1L3MBTL1USP2ALOX15 | |
| SCHEMBL15973796 | 0.76 | THRB (0.39) | ALDH1A1NPSR1TSHRPSMB11PSMA7 | |
| SCHEMBL21531500 | 0.76 | THRB (0.39) | ALDH1A1NPSR1TSHRPSMB11PSMA7 | |
| SCHEMBL10076680 | 0.76 | THRB (0.39) | ALDH1A1NPSR1TSHRPSMB11PSMA7 | |
| SCHEMBL13235977 | 0.74 | PSMB1 (0.38) | PSMB11PSMA7PSMB1PSMA1PSMA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113397-A1 | Imidazo[1,2-a]pyridine derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2005-05-26 | — | — | US | disclosed |
| EP-1479681-A1 | IMIDAZO(1,2-a)PYRIDINE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-11-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113397-A1 | Imidazo[1,2-a]pyridine derivative | MANBA, MAN2B1, ERG28 | ALDH1A1 2550/4885NPSR1 1531/4885L3MBTL1 3913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.