Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PSMB11 | A5LHX3 | 4/20 | 0.33 |
| ▸ | PSMA7 | O14818 | 4/20 | 0.33 |
| ▸ | PSMB1 | P20618 | 4/20 | 0.33 |
| ▸ | PSMA1 | P25786 | 4/20 | 0.33 |
| ▸ | PSMA2 | P25787 | 4/20 | 0.33 |
| ▸ | PSMA3 | P25788 | 4/20 | 0.33 |
| ▸ | PSMA4 | P25789 | 4/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 4/20 | 0.33 |
| ▸ | PSMB9 | P28065 | 4/20 | 0.33 |
| ▸ | PSMA5 | P28066 | 4/20 | 0.33 |
| ▸ | PSMB4 | P28070 | 4/20 | 0.33 |
| ▸ | PSMB6 | P28072 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21531500 | 1.00 | THRB (0.39) | THRBALDH1A1NPSR1TP53SMN1; SMN2 | |
| SCHEMBL15973796 | 1.00 | THRB (0.39) | THRBALDH1A1NPSR1TP53SMN1; SMN2 | |
| SCHEMBL16599630 | 0.89 | MAPT (0.40) | THRBALDH1A1NPSR1TP53SMN1; SMN2 | |
| SCHEMBL15974381 | 0.89 | MAPT (0.40) | THRBALDH1A1NPSR1TP53SMN1; SMN2 | |
| SCHEMBL10835660 | 0.83 | L3MBTL1 (0.41) | ALDH1A1NPSR1TSHRKMT2APSMB11 | |
| SCHEMBL16614399 | 0.81 | MAPT (0.37) | THRBALDH1A1NPSR1TP53SMN1; SMN2 | |
| SCHEMBL2919617 | 0.77 | PSMB1 (0.34) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL6312583 | 0.76 | ALDH1A1 (0.38) | ALDH1A1NPSR1TSHRPSMB11PSMA7 | |
| SCHEMBL10337081 | 0.75 | PSMB11 (0.34) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL10836267 | 0.73 | MAPT (0.39) | THRBALDH1A1TP53SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077989-A1 | CYCLIC IMIDATE LIGANDS | UNIVERSITEIT GENT (BE) | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077989-A1 | CYCLIC IMIDATE LIGANDS | IDH2, CYCS, NAPRT | THRB 1778/4885ALDH1A1 4283/4885NPSR1 3803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.