Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 7/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | UBE2M | P61081 | 7/20 | 0.50 |
| ▸ | DCUN1D1 | Q96GG9 | 7/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL342508 | 0.88 | OPRM1 (0.56) | OPRM1PKMUBE2MDCUN1D1SLC2A1 | |
| SCHEMBL3700749 | 0.84 | OPRD1 (0.55) | OPRM1 | |
| SCHEMBL341621 | 0.83 | PKM (0.65) | OPRM1PKMSLC2A1 | |
| SCHEMBL19027677 | 0.83 | OPRM1 (0.54) | OPRM1PKMUBE2MDCUN1D1 | |
| SCHEMBL341620 | 0.81 | PKM (0.57) | OPRM1PKM | |
| SCHEMBL5329449 | 0.81 | HTR2A (0.59) | OPRM1PKMUBE2MDCUN1D1 | |
| SCHEMBL340169 | 0.81 | HTR2A (0.59) | OPRM1PKMUBE2MDCUN1D1 | |
| SCHEMBL340512 | 0.79 | PKM (0.65) | OPRM1PKM | |
| SCHEMBL18469946 | 0.79 | OPRM1 (0.57) | OPRM1PKMTMEM97 | |
| SCHEMBL4981928 | 0.78 | CCR5 (0.56) | PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014757-A1 | Azacyclic compounds | ANDERSSON CARL-MAGNUS A (DK) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014757-A1 | Azacyclic compounds | HTR6, TPMT, HNMT | OPRM1 210/4885PKM 3533/4885UBE2M 3969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.