Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.32 |
| ▸ | LOX | P28300 | 2/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.30 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27261887 | 0.88 | NUDT1 (0.39) | NUDT1BACE1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2037492 | 0.81 | NUDT1 (0.38) | NUDT1BACE1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1365641 | 0.78 | DRD2 (0.42) | HTR2CDRD2DRD4DRD3NOS3 | |
| SCHEMBL1365449 | 0.71 | NOTUM (0.31) | HTR2C | |
| SCHEMBL16956564 | 0.70 | SLC6A2 (0.40) | NUDT1BACE1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6485019 | 0.70 | TPSAB1 (0.42) | LOXL2DRD2 | |
| SCHEMBL16971226 | 0.70 | MTNR1A (0.41) | — | |
| SCHEMBL3208274 | 0.70 | HTR2C (0.60) | SLC6A2SLC6A4HTR2C | |
| SCHEMBL8276530 | 0.68 | HTR2C (0.53) | SLC6A2SLC6A4SLC6A3HTR2C | |
| SCHEMBL5543574 | 0.67 | GRM7 (0.39) | SLC6A2SLC6A4SLC6A3HTR2CNOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050228018-A1 | Chemical compounds | AVENTIS PHARMACEUTICALS INC. (US) | 2005-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050228018-A1 | Chemical compounds | CMA1, TPSB2, TPSG1 | NUDT1 1660/4885BACE1 229/4885SLC6A2 1657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.