Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 1/20 | 0.66 |
| ▸ | MPL | P40238 | 2/20 | 0.62 |
| ▸ | CTRC | Q99895 | 2/20 | 0.62 |
| ▸ | BRD4 | O60885 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31222680 | 1.00 | CTRB1 (0.66) | CTRB1MPLCTRCBRD4KMT2A | |
| SCHEMBL692673 | 0.85 | BRD4 (0.62) | CTRB1MPLCTRCBRD4KMT2A | |
| SCHEMBL6126114 | 0.85 | BRD4 (0.62) | CTRB1MPLCTRCBRD4KMT2A | |
| SCHEMBL1136824 | 0.85 | BRD4 (0.62) | CTRB1MPLCTRCBRD4KMT2A | |
| SCHEMBL185164 | 0.84 | BRD4 (0.60) | CTRB1MPLCTRCBRD4KMT2A | |
| SCHEMBL185165 | 0.84 | BRD4 (0.60) | CTRB1MPLCTRCBRD4KMT2A | |
| SCHEMBL4811412 | 0.84 | BRD4 (0.60) | CTRB1MPLCTRCBRD4KMT2A | |
| SCHEMBL31300193 | 0.81 | MPL (0.65) | CTRB1MPLCTRCKMT2AMEN1 | |
| SCHEMBL4419746 | 0.81 | MPL (0.65) | CTRB1MPLCTRCKMT2AMEN1 | |
| SCHEMBL14081232 | 0.81 | CTRB1 (0.76) | CTRB1MPLCTRCKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050276764-A1 | Topical use of bis-arylimidazo[1,2-a]thiolane derivatives | BEIERSDORF AG | 2005-12-15 | — | — | US | disclosed |
| US-4968351-A | LAKING | THE MEARL CORPORATION (US) | 1990-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050276764-A1 | Topical use of bis-arylimidazo[1,2-a]thiolane derivatives | ITCH, TRPA1, TPH1 | CTRB1 744/4885MPL 3559/4885CTRC 1639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.