Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19798395 | 0.71 | RIPK1 (0.53) | RIPK1LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL9317468 | 0.68 | AOC3 (0.36) | RIPK1KDM4EL3MBTL1AOC3ALDH1A1 | |
| SCHEMBL6184942 | 0.68 | NR1H2 (0.36) | RIPK1LMNAALDH1A1KMT2A | |
| SCHEMBL9865740 | 0.68 | KDM4E (0.50) | RIPK1LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL28412066 | 0.66 | RIPK1 (0.34) | RIPK1LMNAALDH1A1CYP1A2KMT2A | |
| SCHEMBL16155387 | 0.65 | AOC3 (0.59) | RIPK1LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL1154790 | 0.65 | LMNA (0.58) | RIPK1LMNAKDM4EL3MBTL1AOC3 | |
| Benzene SCHEMBL27821286 | 0.65 | LMNA (0.58) | RIPK1LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL6689030 | 0.65 | LMNA (0.58) | RIPK1LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL4416648 | 0.65 | LMNA (0.58) | RIPK1LMNAKDM4EL3MBTL1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050096360-A1 | Inhibitors of semicarbazide-sensitive amine oxidase (SSAO) and VAP-1 mediated adhesion useful for treatment of diseases | LA JOLLA PHARMACEUTICALS COMPANY | 2005-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050096360-A1 | Inhibitors of semicarbazide-sensitive amine oxidase (SSAO) and VAP-1 mediated adhesion useful for treatment of diseases | VCAM1, AOC2, AOC3 | RIPK1 1836/4885LMNA 4496/4885KDM4E 1438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.