SCHEMBL6689030

SCHEMBL6689030

COC[C@H](O)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.58
KDM4E B2RXH2 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
MAPT P10636 1/20 0.48
AOC3 Q16853 5/20 0.48
RIPK1 Q13546 1/20 0.48
ALDH1A1 P00352 1/20 0.45
HPGD P15428 1/20 0.43
GAA P10253 1/20 0.43
TSHR P16473 1/20 0.43
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL27821286 1.00 LMNA (0.58) LMNAKDM4EL3MBTL1MAPTAOC3
SCHEMBL1154790 1.00 LMNA (0.58) LMNAKDM4EL3MBTL1MAPTAOC3
SCHEMBL4416648 1.00 LMNA (0.58) LMNAKDM4EL3MBTL1MAPTAOC3
SCHEMBL12222364 0.86 LMNA (0.48) LMNAKDM4EL3MBTL1MAPTAOC3
SCHEMBL14758666 0.83 RIPK1 (0.55) LMNAKDM4EL3MBTL1AOC3RIPK1
SCHEMBL1779384 0.83 RIPK1 (0.55) LMNAKDM4EL3MBTL1AOC3RIPK1
SCHEMBL4426990 0.81 LMNA (0.56) LMNAKDM4EL3MBTL1AOC3RIPK1
SCHEMBL5609841 0.81 RIPK1 (0.53) LMNAKDM4EL3MBTL1AOC3RIPK1
SCHEMBL18530454 0.80 LMNA (0.43) LMNAKDM4EL3MBTL1MAPTAOC3
SCHEMBL8257890 0.80 ALDH1A1 (0.49) LMNAKDM4EMAPTAOC3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12509417-B2 Enantioselective process SYNGENTA CROP PROTECTION AG (CH) 2025-12-30 US disclosed
CN-113195460-B Enantioselective process 先正达农作物保护股份公司 2024-07-19 CN disclosed
US-20230331737-A1 MTORC1 MODULATORS AND USES THEREOF AEOVIAN PHARMACEUTICALS, INC. 2023-10-19 US disclosed
EP-3877372-B1 ENANTIOSELECTIVE REDUCTION OF OXIME-DERIVATIVES INVOLVING IRIDIUM BASED CATALYSTS SYNGENTA CROP PROTECTION AG (CH) 2023-08-02 EP disclosed
US-20220106263-A1 ENANTIOSELECTIVE PROCESS SYNGENTA CROP PROTECTION AG (CH) 2022-04-07 US disclosed
US-11230557-B2 mTORC modulators and uses thereof AEOVIAN PHARMACEUTICALS, INC. (US) 2022-01-25 US disclosed
EP-3877372-A1 ENANTIOSELECTIVE PROCESS Syngenta Crop Protection AG (CH) 2021-09-15 EP disclosed
CN-113195460-A Enantioselective process 先正达农作物保护股份公司 2021-07-30 CN disclosed
US-11021492-B2 mTORC modulators and uses thereof AEOVIAN PHARMACEUTICALS, INC. (US) 2021-06-01 US disclosed
US-20210008041-A1 MTORC MODULATORS AND USES THEREOF AEOVIAN PHARMACEUTICALS, INC. 2021-01-14 US disclosed
US-20080228008-A1 Substituted Cyclohexanones FIRMENICH SA (CH) 2008-09-18 US disclosed
US-20080228008-A1 Substituted Cyclohexanones FIRMENICH SA (CH) 2008-09-18 US disclosed
US-7332633-B2 Process for the preparation of optically active cyclohexenones FIRMENICH SA (CH) 2008-02-19 US disclosed
US-7332633-B2 Process for the preparation of optically active cyclohexenones FIRMENICH SA (CH) 2008-02-19 US disclosed
WO-2007010483-A1 SUBSTITUTED CYCLOHEXANONES FIRMENICH SA (CH) 2007-01-25 WO disclosed
WO-2004106269-A1 METHOD FOR PRODUCING SUBSTITUTED SHIRAL DIOLS AND DIOL-ANALOGOUS DERIVATIVES DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) 2004-12-09 WO disclosed
US-20030171544-A1 Alcohol dehydrogenase and use thereof DEGUSSA AG (DE) 2003-09-11 US disclosed
US-20030045727-A1 Process for preparing optically active secondary alcohols having nitrogenous or oxygenic functional groups ASAHI KASEI KABUSHIKI KAISHA (JP) 2003-03-06 US disclosed
EP-1254885-A1 PROCESS FOR PREPARING OPTICALLY ACTIVE SECONDARY ALCOHOLS HAVING NITROGENOUS OR OXYGENIC FUNCTIONAL GROUPS Asahi Kasei Kabushiki Kaisha (JP) 2002-11-06 EP disclosed
EP-1241263-A1 Alcohol dehydrogenase and uses therefor Degussa AG (DE) 2002-09-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12509417-B2 Enantioselective process HCCS, AOC3, CYP8B1 LMNA 1672/4885KDM4E 2012/4885L3MBTL1 1082/4885
US-20220106263-A1 ENANTIOSELECTIVE PROCESS CYP11B2, CYP2E1, CYP2F1 LMNA 4787/4885KDM4E 576/4885L3MBTL1 4624/4885
US-20210008041-A1 MTORC MODULATORS AND USES THEREOF MTOR, RICTOR, RPTOR LMNA 4444/4885KDM4E 1617/4885L3MBTL1 1721/4885
US-11230557-B2 mTORC modulators and uses thereof MTOR, RICTOR, RPTOR LMNA 4444/4885KDM4E 1617/4885L3MBTL1 1721/4885
US-20230331737-A1 MTORC1 MODULATORS AND USES THEREOF MTOR, RPTOR, RICTOR LMNA 4711/4885KDM4E 1611/4885L3MBTL1 694/4885
US-20030171544-A1 Alcohol dehydrogenase and use thereof ADH5, ADH1A, ADH1C LMNA 4722/4885KDM4E 2461/4885L3MBTL1 2989/4885
US-20080228008-A1 Substituted Cyclohexanones NQO1, CYP2J2, CBR3 LMNA 1007/4885KDM4E 1219/4885L3MBTL1 4821/4885
US-20030045727-A1 Process for preparing optically active secondary alcohols having nitrogenous or oxygenic functional groups ADH1A, ADH5, ADH1C LMNA 3712/4885KDM4E 3774/4885L3MBTL1 4559/4885
US-11021492-B2 mTORC modulators and uses thereof MTOR, RICTOR, RPTOR LMNA 4444/4885KDM4E 1617/4885L3MBTL1 1721/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.