SCHEMBL1154790

SCHEMBL1154790

COCC(O)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.58
KDM4E B2RXH2 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
MAPT P10636 1/20 0.48
AOC3 Q16853 5/20 0.48
RIPK1 Q13546 1/20 0.48
ALDH1A1 P00352 1/20 0.45
HPGD P15428 1/20 0.43
GAA P10253 1/20 0.43
TSHR P16473 1/20 0.43
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL27821286 1.00 LMNA (0.58) LMNAKDM4EL3MBTL1MAPTAOC3
SCHEMBL6689030 1.00 LMNA (0.58) LMNAKDM4EL3MBTL1MAPTAOC3
SCHEMBL4416648 1.00 LMNA (0.58) LMNAKDM4EL3MBTL1MAPTAOC3
SCHEMBL12222364 0.86 LMNA (0.48) LMNAKDM4EL3MBTL1MAPTAOC3
SCHEMBL14758666 0.83 RIPK1 (0.55) LMNAKDM4EL3MBTL1AOC3RIPK1
SCHEMBL1779384 0.83 RIPK1 (0.55) LMNAKDM4EL3MBTL1AOC3RIPK1
SCHEMBL4426990 0.81 LMNA (0.56) LMNAKDM4EL3MBTL1AOC3RIPK1
SCHEMBL5609841 0.81 RIPK1 (0.53) LMNAKDM4EL3MBTL1AOC3RIPK1
SCHEMBL18530454 0.80 LMNA (0.43) LMNAKDM4EL3MBTL1MAPTAOC3
SCHEMBL8257890 0.80 ALDH1A1 (0.49) LMNAKDM4EMAPTAOC3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250179233-A1 PROCESS AND CATALYSTS FOR HYDROGEN MEDIATED ANIONIC COPOLYMERIZATION OF CONJUGATED DIENES AND LIQUID COPOLYMERS THEREOF ALBEMARLE CORPORATION (US) 2025-06-05 US claimed
EP-4486808-A2 PROCESS AND CATALYSTS FOR HYDROGEN MEDIATED ANIONIC COPOLYMERIZATION OF CONJUGATED DIENES AND LIQUID COPOLYMERS THEREOF ALBEMARLE CORPORATION (US) 2025-01-08 EP claimed
CN-119137172-A Process and catalyst for hydrogen-mediated anionic copolymerization of conjugated dienes and liquid copolymers thereof 雅宝公司 2024-12-13 CN claimed
WO-2023168218-A2 PROCESS AND CATALYSTS FOR HYDROGEN MEDIATED ANIONIC COPOLYMERIZATION OF CONJUGATED DIENES AND LIQUID COPOLYMERS THEREOF ALBEMARLE CORPORATION (US) 2023-09-07 WO claimed
CN-102753619-B Phenolic resin binder composition JINAN SHENGQUAN GROUP SHARE HOLDING Co.,Ltd. (CN) 2014-10-01 CN claimed
EP-1756191-B1 DERIVATIZED POLYHYDROXYSTYRENES WITH A NOVOLAK TYPE STRUCTURE AND PROCESSES FOR PREPARING THE SAME DUPONT ELECTRONIC POLYMERS L P (US) 2012-09-19 EP claimed
US-20260000642-A1 PYRROLES AND IMIDAZOLES AS BET PROTEIN INHIBITORS TAY THERAPEUTICS LTD (GB) 2026-01-01 US disclosed
US-12509417-B2 Enantioselective process SYNGENTA CROP PROTECTION AG (CH) 2025-12-30 US disclosed
US-12435078-B2 Pyridazinones and methods of use thereof GFB (ABC), LLC (US) 2025-10-07 US disclosed
US-20250263370-A1 PYRROLES AND IMIDAZOLES AS BET PROTEIN INHIBITORS Tay Therapeutics Limited (GB) 2025-08-21 US disclosed
US-20250179233-A1 PROCESS AND CATALYSTS FOR HYDROGEN MEDIATED ANIONIC COPOLYMERIZATION OF CONJUGATED DIENES AND LIQUID COPOLYMERS THEREOF ALBEMARLE CORPORATION (US) 2025-06-05 US disclosed
EP-4558224-A1 PYRROLES AND IMIDAZOLES AS BET PROTEIN INHIBITORS Tay Therapeutics Limited (GB) 2025-05-28 EP disclosed
WO-2025072395-A1 TRIAZOLOPYRIDINYL COMPOUNDS AS KINASE INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-04-03 WO disclosed
EP-0320096-B1 PROCESS FOR ASYMMETRICALLY REDUCING CARBONYL COMPOUNDS AJINOMOTO CO., INC. (JP) 1991-08-21 EP disclosed
US-4943652-A Process for asymmetrically reducing carbonyl compounds AJINOMOTO CO., INC. (JP) 1990-07-24 US disclosed
EP-0226641-B1 OXODIAZINE COMPOUNDS YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1989-10-18 EP disclosed
EP-0320096-A1 Process for asymmetrically reducing carbonyl compounds AJINOMOTO CO., INC. (JP) 1989-06-14 EP disclosed
US-4713381-A ANTICOAGULANTS, ANALGESICS, ANTIINFLAMMATORY AGENT YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1987-12-15 US disclosed
EP-0226641-A1 OXODIAZINE COMPOUNDS. YOSHITOMI PHARMACEUTICAL (JP) 1987-07-01 EP disclosed
WO-1986007059-A2 OXODIAZINE COMPOUNDS YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1986-12-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12509417-B2 Enantioselective process HCCS, AOC3, CYP8B1 LMNA 1672/4885KDM4E 2012/4885L3MBTL1 1082/4885
US-12435078-B2 Pyridazinones and methods of use thereof PDXK, ATP6V1B1, REN LMNA 715/4885KDM4E 3899/4885L3MBTL1 4848/4885
US-20260000642-A1 PYRROLES AND IMIDAZOLES AS BET PROTEIN INHIBITORS BET1, BRD4, PHKB LMNA 3175/4885KDM4E 947/4885L3MBTL1 4090/4885
US-20250263370-A1 PYRROLES AND IMIDAZOLES AS BET PROTEIN INHIBITORS BET1, PHKB, BRD4 LMNA 4331/4885KDM4E 309/4885L3MBTL1 3923/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.