Dimetridazole

Dimetridazole

SCHEMBL63278

Cc1ncc([N+](=O)[O-])n1C

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.59
ALDH1A1 P00352 3/20 0.59
MAPK1 P28482 2/20 0.59
THRB P10828 2/20 0.59
TSHR P16473 1/20 0.59
CA1 P00915 5/20 0.53
CA2 P00918 5/20 0.53
CA9 Q16790 5/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
ATM Q13315 1/20 0.51
CA12 O43570 4/20 0.49
GLA P06280 1/20 0.49
GAA P10253 1/20 0.49
CHRM1 P11229 1/20 0.47
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
KDM4E B2RXH2 1/20 0.45
CYP2C19 P33261 1/20 0.45
KMT2A Q03164 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimetridazole SCHEMBL10455000 0.98 LMNA (0.57) LMNAALDH1A1MAPK1THRBTSHR
Dimetridazole SCHEMBL29886852 0.86 LMNA (0.50) LMNAALDH1A1MAPK1THRBTSHR
Secnidazole SCHEMBL28208800 0.81 MAPK1 (0.86) LMNAALDH1A1MAPK1THRBTSHR
SCHEMBL11619443 0.78 LMNA (0.46) LMNAALDH1A1MAPK1THRBTSHR
SCHEMBL20375687 0.78 LMNA (0.50) LMNAALDH1A1MAPK1THRBTSHR
SCHEMBL19402556 0.78 LMNA (0.53) LMNAALDH1A1MAPK1THRBTSHR
SCHEMBL11831842 0.78 LMNA (0.46) LMNAALDH1A1MAPK1THRBTSHR
SCHEMBL9490979 0.78 ALDH1A1 (0.53) LMNAALDH1A1MAPK1THRBTSHR
SCHEMBL27704271 0.78 ALDH1A1 (0.53) LMNAALDH1A1MAPK1THRBTSHR
SCHEMBL3281642 0.78 LMNA (0.49) LMNAALDH1A1MAPK1THRBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1750 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078296-A1 SUSTAINED-RELEASE SCALE INHIBITORS Materials Engineering and Technical Support Services (US) 2026-03-19 US claimed
EP-4680248-A1 PRODUCTS OF MANUFACTURE AND THERAPEUTIC COMPOSITIONS FOR TREATING, AMELIORATING OR PREVENTING VIRAL INFECTIONS AND METHODS FOR MAKING AND USING THEM Topelia Aust Limited (ACN 652 771 670) (AU) 2026-01-21 EP claimed
US-12496548-B2 Hydrophobic MOF-based porous liquid carbon capture absorbent and preparation method therefor HUANENG CLEAN ENERGY RESEARCH INSTITUTE (CN) 2025-12-16 US claimed
US-20250268934-A1 Compositions and Methods for the Treatment of Bacterial Vaginosis WAYNE STATE UNIVERSITY (US) 2025-08-28 US claimed
WO-2025085790-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF VAGINITIS WAYNE STATE UNIVERSITY (US) 2025-04-24 WO claimed
US-12274830-B2 Nitric oxide inhalation therapy for infants with bronchiolitis BEYOND AIR LTD (IL) 2025-04-15 US claimed
EP-4507693-A2 COMPOSITIONS AND METHODS FOR THE TREATMENT OF BACTERIAL VAGINOSIS Wayne State University (US) 2025-02-19 EP claimed
US-20250032455-A1 NITROIMIDAZOLE FORMULATIONS IRP Health Pty Ltd (AU) 2025-01-30 US claimed
US-12171748-B2 Nitroimidazole formulations IRP Health Pty Ltd (AU) 2024-12-24 US claimed
US-20240382899-A1 Hydrophobic MOF-Based Porous Liquid Carbon Capture Absorbent and Preparation Method Therefor SHANGHAI SHIDONGKOU NO. 2 POWER PLANT HUANENG INTERNATIONAL POWER CO. LTD (CN) 2024-11-21 US claimed
US-4920141-A MIXTURE OF WATER SOLUBLE SALT OF METRONIDAZOLE, DIMETRIDAZOLE, SECNIDAZOLE OR IPRONIDAZOLE AND GLUTARALDEHYDE; INDUSTRIAL WATER TREATMENT PETROLITE CORPORATION (US) 1990-04-24 US claimed
US-4701331-A Non-dusty blends of meals or flours with active principles for use in fodder production DOX-AL ITALIA SPA (IT) 1987-10-20 US claimed
US-4662905-A REACTION PRODUCT OF COPPER SALT AND AN IMIDAZOLE, PYRAZOLE, TRIAZOLE, OR TETRAZOLE Itaru Todoriki, Director of Agency of Industrial Science and Technology (JP) 1987-05-05 US claimed
EP-0072919-B1 PROCESS FOR THE PREPARATION OF 1,2-DIMETHYL-5-NITROIMIDAZOLE OF HIGH PURITY BASF Aktiengesellschaft (DE) 1986-01-08 EP claimed
EP-0146738-A2 Antimicrobial animal feed additive compositions AMERICAN CYANAMID COMPANY (US) 1985-07-03 EP claimed
EP-0043922-B1 PROCESS FOR PREPARING 1,2-DIMETHYL-5-NITROIMIDAZOLE BASF Aktiengesellschaft (DE) 1984-09-19 EP claimed
EP-0072919-A1 Process for the preparation of 1,2-dimethyl-5-nitroimidazole of high purity BASF Aktiengesellschaft (DE) 1983-03-02 EP claimed
US-4339448-A Imidazole-copper complex compounds and fungicides containing them BASF AKTIENGESELLSCHAFT (DE) 1982-07-13 US claimed
EP-0043922-A1 Process for preparing 1,2-dimethyl-5-nitroimidazole BASF Aktiengesellschaft (DE) 1982-01-20 EP claimed
US-3952007-A Processes for preparing 5-nitro-1-methyl-2-(2-dialkylaminovinyl)-imidazole and 5-nitro-1-methyl-2-imidazolyl carboxaldehyde SCHERING AKTIENGESELLSCHAFT (DT) 1976-04-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078296-A1 SUSTAINED-RELEASE SCALE INHIBITORS CEL, TST, CD44 LMNA 3849/4885ALDH1A1 1392/4885MAPK1 4020/4885
US-12171748-B2 Nitroimidazole formulations PHB1, COX5B, CYP3A5 LMNA 3271/4885ALDH1A1 3471/4885MAPK1 3643/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.