Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.64 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.54 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.53 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.53 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.53 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30792366 | 0.87 | FFAR1 (0.81) | FFAR1F2RL1POLBFFAR4ALDH1A1 | |
| SCHEMBL274471 | 0.87 | FFAR1 (0.81) | FFAR1F2RL1POLBFFAR4ALDH1A1 | |
| SCHEMBL3196104 | 0.84 | MEN1 (0.62) | FFAR1F2RL1POLBPLAAT3PLAAT5 | |
| SCHEMBL8880193 | 0.84 | SMN1; SMN2 (0.57) | F2RL1SMN1; SMN2ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6895397 | 0.82 | SMN1; SMN2 (0.56) | F2RL1SMN1; SMN2ALDH1A1MEN1KMT2A | |
| Anisole SCHEMBL31387002 | 0.82 | FFAR1 (0.74) | FFAR1F2RL1FFAR4PLAAT3PLAAT5 | |
| SCHEMBL1566761 | 0.82 | FFAR1 (0.73) | FFAR1F2RL1POLBFFAR4ALDH1A1 | |
| Phenyl Propionic Acid SCHEMBL2153185 | 0.80 | KEAP1 (0.70) | FFAR1FFAR4PLAAT5PLAAT4SMN1; SMN2 | |
| Anisole SCHEMBL30496784 | 0.80 | FFAR1 (0.70) | FFAR1F2RL1FFAR4PLAAT3PLAAT5 | |
| SCHEMBL524586 | 0.80 | KMT2A (0.64) | FFAR1F2RL1SMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1595936-B1 | COMPOSITION FOR EXTERNAL USE | VITAMIN C60 BIORES CORP (JP) | 2011-10-19 | — | — | EP | claimed |
| US-20060134095-A1 | Antioxidative composition and composition for external use | VITAMIN C60 BIORESEARCH CORPORATION (JP) | 2006-06-22 | — | — | US | claimed |
| EP-1595936-A1 | ANTIOXIDATIVE COMPOSITION AND COMPOSITION FOR EXTERNAL USE | MITSUBISHI CORPORATION (JP) | 2005-11-16 | — | — | EP | claimed |
| US-5585090-A | MIXTURE OF METAL OXIDE FLAKE AND ULTRAVIOLET ABSORBENTENCAPSULATED POLYMER | THE PROCTER & GAMBLE COMPANY (US) | 1996-12-17 | — | — | US | claimed |
| EP-0503922-B1 | Cosmetics having photoprotection properties | MAX FACTOR KK (JP) | 1995-12-20 | — | — | EP | claimed |
| EP-0503922-A2 | Cosmetics having photoprotection properties | MAX FACTOR K.K. (JP) | 1992-09-16 | — | — | EP | claimed |
| US-12605315-B2 | External skin preparation | KAO CORPORATION (JP) | 2026-04-21 | — | — | US | disclosed |
| US-12551424-B2 | Oil-in-water type emulsification composition containing UV wavelength conversion substance | SHISEIDO COMPANY, LTD. (JP) | 2026-02-17 | — | — | US | disclosed |
| US-12440431-B2 | Cosmetic comprising ultraviolet wavelength conversion substance | SHISEIDO COMPANY, LTD. (JP) | 2025-10-14 | — | — | US | disclosed |
| US-12419818-B2 | External preparation | KAO CORPORATION (JP) | 2025-09-23 | — | — | US | disclosed |
| US-12414977-B2 | Method of administering seaberry and saw palmetto extracts to inhibit 5α-reductase activity | ORYZA OIL & FAT CHEMICAL CO., LTD. (JP) | 2025-09-16 | — | — | US | disclosed |
| US-20250268972-A1 | 5a-REDUCTASE INHIBITOR | ORYZA OIL & FAT CHEMICAL CO., LTD. (JP) | 2025-08-28 | — | — | US | disclosed |
| US-20250255791-A1 | POWDER COSMETIC CONTAINING ULTRAVIOLET WAVELENGTH-CONVERTING SUBSTANCE, AND METHOD FOR PRODUCING SAME | SHISEIDO COMPANY, LTD. (JP) | 2025-08-14 | — | — | US | disclosed |
| EP-1364943-A1 | NOVEL CYSTINE DERIVATIVES AND INHIBITORS FOR THE ACTIVATION OF INFLAMMATORY FACTORS | Ajinomoto Co., Inc. (JP) | 2003-11-26 | — | — | EP | disclosed |
| EP-1213006-A1 | COSMETICS | KANEBO, LTD. (JP) | 2002-06-12 | — | — | EP | disclosed |
| JP-2000136122-A | SKIN LOTION | KOSE CORP | 2000-05-16 | — | — | JP | disclosed |
| JP-2000136123-A | SKIN LOTION | KOSE CORP | 2000-05-16 | — | — | JP | disclosed |
| US-5585090-A | MIXTURE OF METAL OXIDE FLAKE AND ULTRAVIOLET ABSORBENTENCAPSULATED POLYMER | THE PROCTER & GAMBLE COMPANY (US) | 1996-12-17 | — | — | US | disclosed |
| EP-0503922-B1 | Cosmetics having photoprotection properties | MAX FACTOR KK (JP) | 1995-12-20 | — | — | EP | disclosed |
| EP-0503922-A2 | Cosmetics having photoprotection properties | MAX FACTOR K.K. (JP) | 1992-09-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12605315-B2 | External skin preparation | TLR5, CUTA, TLR3 | FFAR1 29/4885F2RL1 2027/4885POLB 261/4885 |
| US-20060134095-A1 | Antioxidative composition and composition for external use | GPX4, GPX1, SOD1 | FFAR1 1512/4885F2RL1 3874/4885POLB 1227/4885 |
| US-12551424-B2 | Oil-in-water type emulsification composition containing UV wavelength conversion substance | PCNA, CD14, TP53 | FFAR1 3769/4885F2RL1 4284/4885POLB 64/4885 |
| US-12419818-B2 | External preparation | CUTA, ALOX15, HSF1 | FFAR1 466/4885F2RL1 3558/4885POLB 154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.