SCHEMBL633169

SCHEMBL633169

COc1ccc(/C=C/C(=O)c2ccc(O)cc2O)cc1O

nearest known ligand 0.85

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.85
KMT2A Q03164 6/20 0.85
ABCG2 Q9UNQ0 4/20 0.85
CYP3A4 P08684 4/20 0.85
HPGD P15428 4/20 0.85
TDP1 Q9NUW8 3/20 0.85
TP53 P04637 3/20 0.85
MAPT P10636 3/20 0.85
ALOX15 P16050 3/20 0.85
MAPK1 P28482 3/20 0.85
ALDH1A1 P00352 2/20 0.85
ALOX12 P18054 1/20 0.85
SMN1; SMN2 Q16637 1/20 0.85
NFKB1 P19838 4/20 0.81
NFKB2 Q00653 3/20 0.81
RELA Q04206 3/20 0.81
CTSL P07711 2/20 0.79
MAOB P27338 2/20 0.72
TUBB1 Q9H4B7 1/20 0.72
LMNA P02545 3/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL633170 1.00 MEN1 (0.85) MEN1KMT2AABCG2CYP3A4HPGD
SCHEMBL25206351 1.00 MEN1 (0.85) MEN1KMT2AABCG2CYP3A4HPGD
SCHEMBL30383806 0.92 ABCG2 (1.00) MEN1KMT2AABCG2CYP3A4HPGD
SCHEMBL25217986 0.92 ABCG2 (1.00) MEN1KMT2AABCG2CYP3A4HPGD
SCHEMBL633470 0.92 ABCG2 (1.00) MEN1KMT2AABCG2CYP3A4HPGD
SCHEMBL633469 0.92 ABCG2 (1.00) MEN1KMT2AABCG2CYP3A4HPGD
SCHEMBL25234197 0.91 ABCG2 (0.85) MEN1KMT2AABCG2CYP3A4HPGD
Ethane SCHEMBL25195312 0.91 ABCG2 (0.97) MEN1KMT2AABCG2CYP3A4HPGD
SCHEMBL21527688 0.91 ABCG2 (0.85) MEN1KMT2AABCG2CYP3A4HPGD
SCHEMBL21527689 0.91 ABCG2 (0.85) MEN1KMT2AABCG2CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4655410-A2 O-METHYLATION OF PHENOLIC SUBSTANCES VIA FUNGAL O-METHYLTRANSFERASE Symrise AG (DE) 2025-12-03 EP claimed
WO-2024156359-A1 O-METHYLATION OF PHENOLIC SUBSTANCES VIA FUNGAL O-METHYLTRANSFERASE SYMRISE AG (DE) 2024-08-02 WO claimed
WO-2024156879-A2 O-METHYLATION OF PHENOLIC SUBSTANCES VIA FUNGAL O-METHYLTRANSFERASE SYMRISE AG (DE) 2024-08-02 WO claimed
US-20240150797-A1 BIOCATALYTICAL PRODUCTION OF DIHYDROCHALCONES SYMRISE AG (DE) 2024-05-09 US claimed
EP-4301865-A1 BIOCATALYTICAL PRODUCTION OF DIHYDROCHALCONES Symrise AG (DE) 2024-01-10 EP claimed
US-20230099567-A1 COMPOSITION FOR TREATMENT, PREVENTION, OR AMELIORATION OF LYMPHEDEMA RAPPELER CO., LTD. (KR) 2023-03-30 US claimed
WO-2022184248-A1 BIOCATALYTICAL PRODUCTION OF DIHYDROCHALCONES SYMRISE AG (DE) 2022-09-09 WO claimed
US-9877946-B2 Method for treating, managing, inhibiting, or preventing obesity Research & Business Foundation Sungkyunkwan University (KR) 2018-01-30 US claimed
US-20170087126-A1 COMPOSITION FOR INDUCING DIFFERENTIATION INTO BEIGE AND BROWN ADIPOCYTES AND METHOD OF INDUCING THE SAME RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVER SITY (KR) 2017-03-30 US claimed
US-9549908-B2 Composition for inducing differentiation into beige and brown adipocytes and method of inducing the same Research & Business Foundation Sungkyunkwan University, Ltd. (KR) 2017-01-24 US claimed
US-20150374643-A1 COMPOSITION FOR INDUCING DIFFERENTIATION INTO BEIGE AND BROWN ADIPOCYTES AND METHOD OF INDUCING THE SAME Research & Business Foundation Sungkyunkwan University (KR) 2015-12-31 US claimed
EP-1888174-B1 USE OF CHALCONES FOR THE TREATMENT OF VIRAL DISORDERS JOHNSON & JOHNSON CONSUMER (US) 2012-02-22 EP claimed
EP-1888174-A1 USE OF CHALCONES FOR THE TREATMENT OF VIRAL DISORDERS Johnson and Johnson Consumer Companies, Inc. (US) 2008-02-20 EP claimed
WO-2006127539-A1 USE OF CHALCONES FOR THE TREATMENT OF VIRAL DISORDERS JOHNSON & JOHNSON CONSUMER COMPANIES, INC. (US) 2006-11-30 WO claimed
US-20060270614-A1 Use of chalcones for the treatment of viral disorders JOHNSON & JOHNSON CONSUMER COMPANIES, INC. 2006-11-30 US claimed
EP-4747367-A1 NEW ENZYMES FOR THE MANUFACTURING OF 4'-O-METHYLATED PHENOLIC SUBSTANCES Symrise AG (DE) 2026-05-27 EP disclosed
EP-3713561-B1 COMBINATION OF BUTEIN, ISOLIQUIRITIGENIN AND SULFURETIN, AND ITS USE FOR THE TREATMENT OF DIABETES AND ASSOCIATED DISORDERS OTAGO INNOVATION LTD (NZ) 2026-05-06 EP disclosed
EP-0370461-B1 Chalcone derivatives and process for producing the same DAINIPPON INK & CHEMICALS (JP) 1995-06-28 EP disclosed
US-5068364-A Antiulcer agents, antiallergens DAINIPPON INK AND CHEMICALS, INC. (JP) 1991-11-26 US disclosed
EP-0370461-A2 Chalcone derivatives and process for producing the same DAINIPPON INK AND CHEMICALS, INC. (JP) 1990-05-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170087126-A1 COMPOSITION FOR INDUCING DIFFERENTIATION INTO BEIGE AND BROWN ADIPOCYTES AND METHOD OF INDUCING THE SAME FABP4, PLIN1, PRDM7 MEN1 3611/4885KMT2A 2456/4885ABCG2 3473/4885
US-20150374643-A1 COMPOSITION FOR INDUCING DIFFERENTIATION INTO BEIGE AND BROWN ADIPOCYTES AND METHOD OF INDUCING THE SAME FABP4, PLIN1, PRDM7 MEN1 3611/4885KMT2A 2456/4885ABCG2 3473/4885
US-20060270614-A1 Use of chalcones for the treatment of viral disorders HAVCR2, HMGB3, EIF2AK2 MEN1 3326/4885KMT2A 4014/4885ABCG2 3800/4885
US-20230099567-A1 COMPOSITION FOR TREATMENT, PREVENTION, OR AMELIORATION OF LYMPHEDEMA LIPG, LPL, LTA MEN1 4247/4885KMT2A 3466/4885ABCG2 1942/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.