Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5546721 | 0.78 | NOTUM (0.38) | NOTUMALDH1A1KDM4EMAPTHTT | |
| SCHEMBL9625933 | 0.78 | MAPT (0.42) | ALDH1A1HPGDKDM4EMAPTPOLB | |
| SCHEMBL8879382 | 0.78 | MAPT (0.46) | ALDH1A1HPGDKDM4EMAOAMAPT | |
| SCHEMBL7306890 | 0.78 | CHRNB2 (0.42) | ALDH1A1HTTNPC1L3MBTL1 | |
| SCHEMBL5120604 | 0.77 | NOTUM (0.45) | NOTUMALDH1A1MAPTHTTSIGMAR1 | |
| SCHEMBL8625261 | 0.74 | ALDH1A1 (0.41) | ALDH1A1KDM4EMAPTNPSR1MEN1 | |
| SCHEMBL5089483 | 0.72 | CYP11B1 (0.47) | ALDH1A1MAPTNPSR1NPC1CYP1A2 | |
| SCHEMBL5128093 | 0.71 | BCHE (0.38) | NOTUMALDH1A1KDM4EHTTMEN1 | |
| SCHEMBL4473341 | 0.71 | MGLL (0.37) | ALDH1A1MAPTNPC1MAPK1 | |
| SCHEMBL5119689 | 0.66 | CYP19A1 (0.38) | NOTUMALDH1A1MAPTHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 645 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118027085-A | Organic electroluminescent compound and application thereof | 宁波卢米蓝新材料有限公司 | 2024-05-14 | — | — | CN | claimed |
| US-9873705-B2 | Vinylogous thioester compounds and methods of use | THE TRUSTEES OF DARTMOUTH COLLEGE (US) | 2018-01-23 | — | — | US | claimed |
| US-20170152262-A1 | VINYLOGOUS THIOESTER COMPOUNDS AND METHODS OF USE | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-06-01 | — | — | US | claimed |
| EP-2665722-B1 | PROCESS FOR THE PREPARATION OF DIOL SULFONES | DSM SINOCHEM PHARM NL BV (NL) | 2016-08-17 | — | — | EP | claimed |
| WO-2016125086-A1 | PROCESSES FOR THE PREPARATION OF ROSUVASTATIN OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | LAURUS LABS PRIVATE LIMITED (IN) | 2016-08-11 | — | — | WO | claimed |
| EP-2694509-B1 | PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES AS INHIBITORS OF TROPOMYOSIN-RELATED KINASES | PFIZER LTD (GB) | 2016-05-18 | — | — | EP | claimed |
| EP-2334640-B1 | METHODS FOR PRODUCING PARICALCITOL | AZAD PHARMACEUTICAL INGREDIENTS AG (CH) | 2015-12-23 | — | — | EP | claimed |
| US-9212136-B2 | Methods for producing paricalcitol | AZAD PHARMACEUTICALS INGREDIENTS AG (CH) | 2015-12-15 | — | — | US | claimed |
| US-9150562-B2 | Process for the preparation of diol sulfones | DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) | 2015-10-06 | — | — | US | claimed |
| US-9126975-B2 | Process for the preparation of statins in the presence of base | DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) | 2015-09-08 | — | — | US | claimed |
| EP-0026519-B1 | PHOTOGRAPHIC SILVER HALIDE EMULSION MATERIAL CONTAINING AN ANTIFOGGANT PRECURSOR | AGFA-GEVAERT N.V. (BE) | 1983-08-17 | — | — | EP | claimed |
| US-4385178-A | REACTION OF A CEPHALOSPORANIC ACID WITH A THIOL COMPOUND IN THE PRESENCE OF BORON TRIFLUORIDE | TOYAMA CHEMICAL CO., LTD. (JP) | 1983-05-24 | — | — | US | claimed |
| US-4317907-A | ANHYDROUS CONDITIONS IN THE PRESENCE OF BOREN TRIFLUORIDE OR ONE OF ITS COMPLEXES | TOYAMA CHEMICAL CO., LTD. (JP) | 1982-03-02 | — | — | US | claimed |
| US-4317920-A | ANTIRHEUMATIC AGENTS, ANTIINFLAMMATORY AGENTS | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1982-03-02 | — | — | US | claimed |
| EP-0005153-B1 | 4-NITRO-2-TRICHLOROMETHYLPHENYL DISULFIDES, PROCESS FOR THEIR PREPARATION, MEANS CONTAINING THEM AS ACTIVE INGREDIENT AND USE AGAINST MICROORGANISMS | BASF Aktiengesellschaft (DE) | 1982-01-27 | — | — | EP | claimed |
| US-4307175-A | Photographic silver halide emulsion material containing an antifoggant precursor | AGFA-GEVAERT, N.V. (BE) | 1981-12-22 | — | — | US | claimed |
| EP-0026519-A1 | Photographic silver halide emulsion material containing an antifoggant precursor | AGFA-GEVAERT N.V. (BE) | 1981-04-08 | — | — | EP | claimed |
| US-4125611-A | MICROBIOCIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1978-11-14 | — | — | US | claimed |
| US-4052213-A | OXAZOLINONE-2-COMPOUNDS CONTAINING A MERCAPTO GROUP | AGFA-GEVAERT, A.G. (DT) | 1977-10-04 | — | — | US | claimed |
| US-4046574-A | COLOR PHOTOGRAPHIC MATERIAL WITH HOMOPHTHALIMIDE THIOETHER DEVELOPMENT INHIBITOR | AGFA-GEVAERT, AKTIENGESELLSCHAFT (DT) | 1977-09-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170152262-A1 | VINYLOGOUS THIOESTER COMPOUNDS AND METHODS OF USE | ACOT7, LYPLA2, PPT1 | NOTUM 61/4885ALDH1A1 1113/4885HPGD 1461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.