Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.37 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CASP2 | P42575 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27683553 | 1.00 | KDM4E (0.48) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL17076289 | 0.91 | KDM4E (0.41) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL8774992 | 0.91 | KDM4E (0.56) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL8775285 | 0.91 | KDM4E (0.56) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL8775297 | 0.91 | KDM4E (0.56) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL8775294 | 0.91 | KDM4E (0.56) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL8775499 | 0.91 | KDM4E (0.56) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL59429 | 0.91 | KDM4E (0.56) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL907569 | 0.89 | KDM4E (0.52) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL10081668 | 0.85 | KDM4E (0.70) | KDM4EMAPK1HIF1APAOXADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006069366-A1 | METHODS OF PROTEIN PROFILING BY THIOLATION | INTEL CORPORATION (US) | 2006-06-29 | — | — | WO | claimed |
| US-20060134694-A1 | Methods of protein profiling by thiolation | INTEL CORPORATION (US) | 2006-06-22 | — | — | US | claimed |
| EP-4094748-B1 | DENTAL MATERIALS BASED ON REDOX SYSTEMS WITH OLIGOMERIC CUMOLHYDROPEROXIDE DERIVATIVES | IVOCLAR VIVADENT AG (LI) | 2023-09-20 | — | — | EP | disclosed |
| US-11618799-B2 | Composite with reduced polymerization shrinkage stress | IVOCLAR VIVADENT AG (LI) | 2023-04-04 | — | — | US | disclosed |
| EP-4039220-B1 | DENTAL MATERIALS ON THE BASIS OF POLYMERISABLE THIOUREA DERIVATIVES | IVOCLAR VIVADENT AG (LI) | 2022-12-28 | — | — | EP | disclosed |
| US-11357709-B2 | Dental materials based on redox systems with low-odour cumene hydroperoxide derivatives | IVOCLAR VIVADENT AG (LI) | 2022-06-14 | — | — | US | disclosed |
| EP-3692975-B1 | DENTAL MATERIALS WITH IMPROVED SETTING | IVOCLAR VIVADENT AG (LI) | 2022-05-18 | — | — | EP | disclosed |
| US-20220002461-A1 | Composite With Reduced Polymerization Shrinkage Stress | IVOCLAR VIVADENT AG (LI) | 2022-01-06 | — | — | US | disclosed |
| EP-3932383-A1 | COMPOSITES HAVING REDUCED POLYMERIZATION SHRINKAGE STRESS | Ivoclar Vivadent AG (LI) | 2022-01-05 | — | — | EP | disclosed |
| US-11141354-B2 | Dental materials with improved mechanical properties | IVOCLAR VIVADENT AG (LI) | 2021-10-12 | — | — | US | disclosed |
| US-11141356-B2 | Dental materials with improved setting behaviour | IVOCLAR VIVADENT AG (LI) | 2021-10-12 | — | — | US | disclosed |
| EP-2103296-A1 | Polymer-coated glass filler for use in dental material | Ivoclar Vivadent AG (LI) | 2009-09-23 | — | — | EP | disclosed |
| US-20090139433-A1 | DENTAL MATERIALS BASED ON ALKYLENEDIAMINE-N,N,N',N'- TETRAACETIC ACID- (METH)ACRYLAMIDES | IVOCLAR VIVADENT AG (LI) | 2009-06-04 | — | — | US | disclosed |
| EP-2065363-A1 | Dental materials based on alkylenediamine-N,N,N',N'-tetraacetic acid-(meth)acrylamides | Ivoclar Vivadent AG (LI) | 2009-06-03 | — | — | EP | disclosed |
| WO-2006069366-A1 | METHODS OF PROTEIN PROFILING BY THIOLATION | INTEL CORPORATION (US) | 2006-06-29 | — | — | WO | disclosed |
| US-20060134694-A1 | Methods of protein profiling by thiolation | INTEL CORPORATION (US) | 2006-06-22 | — | — | US | disclosed |
| EP-1374829-B1 | Dental material on the basis of acryloester phosphonic acid | IVOCLAR VIVADENT AG (LI) | 2005-11-02 | — | — | EP | disclosed |
| US-6900251-B2 | Dental materials based on acrylic-ester phosphonic acids | IVOCLAR VIVADENT AG (LI) | 2005-05-31 | — | — | US | disclosed |
| US-20040077754-A1 | Dental materials based on acrylic-ester phosphonic acids | IVOCLAR VIVADENT AG (LI) | 2004-04-22 | — | — | US | disclosed |
| EP-1374829-A1 | Dental material on the basis of acryloester phosphonic acid | Ivoclar Vivadent AG (LI) | 2004-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090139433-A1 | DENTAL MATERIALS BASED ON ALKYLENEDIAMINE-N,N,N',N'- TETRAACETIC ACID- (METH)ACRYLAMIDES | DDAH1, MDN1, NAA15 | KDM4E 3765/4885MAPK1 3224/4885HIF1A 1309/4885 |
| US-11141356-B2 | Dental materials with improved setting behaviour | GPX4, GPX1, TTPA | KDM4E 1947/4885MAPK1 4680/4885HIF1A 400/4885 |
| US-20040077754-A1 | Dental materials based on acrylic-ester phosphonic acids | PHOSPHO1, RER1, PTGER1 | KDM4E 4283/4885MAPK1 202/4885HIF1A 496/4885 |
| US-11357709-B2 | Dental materials based on redox systems with low-odour cumene hydroperoxide derivatives | GPX4, GPX1, AOX1 | KDM4E 4240/4885MAPK1 2387/4885HIF1A 367/4885 |
| US-11141354-B2 | Dental materials with improved mechanical properties | GPX4, GPX1, PRDX3 | KDM4E 3142/4885MAPK1 3687/4885HIF1A 508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.