SCHEMBL633960

SCHEMBL633960

O=C1NC(=O)c2cscc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.48
CASP7 P55210 2/20 0.40
CASP3 P42574 1/20 0.40
CASP2 P42575 1/20 0.40
CASP6 P55212 1/20 0.40
CASP8 Q14790 1/20 0.40
PARP1 P09874 3/20 0.39
PPOX P50336 1/20 0.37
MAOA P21397 4/20 0.34
MAOB P27338 4/20 0.34
PDGFRA P16234 1/20 0.33
FER P16591 1/20 0.33
LTK P29376 1/20 0.33
CDK8 P49336 1/20 0.33
ACVR1 Q04771 1/20 0.33
LRRK2 Q5S007 1/20 0.33
DYRK1B Q9Y463 1/20 0.33
TDP1 Q9NUW8 4/20 0.32
MAPT P10636 4/20 0.32
EGFR P00533 4/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4896875 0.70 ACVR1 (0.61) GSK3BMAOAMAOBPDGFRAFER
SCHEMBL10926488 0.69 MEN1 (0.39) CASP7MAOAMAOBTDP1MAPT
SCHEMBL9674007 0.67 MEN1 (0.37) MAOAMAOBTDP1MAPTMEN1
SCHEMBL3678137 0.67 ESR1 (0.42) ESR1ESR2
SCHEMBL13409576 0.65 CASP3 (0.44) GSK3BCASP7CASP3MAPTMEN1
SCHEMBL15488741 0.65 GSK3B (0.50) GSK3BCASP7CASP3CASP2CASP6
Phthalimide SCHEMBL64 0.65 GSK3B (1.00) GSK3BCASP7CASP3CASP2CASP6
Phthalimide SCHEMBL11040503 0.65 GSK3B (1.00) GSK3BCASP7CASP3CASP2CASP6
SCHEMBL239945 0.65 GSK3B (0.50) GSK3BCASP7CASP3CASP2CASP6
Phthalimide SCHEMBL7771670 0.65 GSK3B (1.00) GSK3BCASP7CASP3CASP2CASP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 293 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12389734-B2 Inverted polymer photovoltaic cell and method for preparation thereof ENI S.P.A. (IT) 2025-08-12 US claimed
US-12364155-B2 Polymer compositions for vertical channel organic electrochemical transistors and complementary logic circuits NORTHWESTERN UNIVERSITY (US) 2025-07-15 US claimed
US-20250098393-A1 MONOLITHIC INTEGRATION OF VERTICAL ELECTROCHEMICAL TRANSISTORS NORTHWESTERN UNIVERSITY 2025-03-20 US claimed
US-20250089430-A1 ORGANIC SOLAR CELLS AND METHODS OF MAKING THE SAME UNIV NEW YORK (US) 2025-03-13 US claimed
US-20250051352-A1 DIARYLOXYBENZOHETERODIAZOLE COMPOUNDS DISUBSTITUTED WITH THIENOTHIOPHENE GROUPS ENI S.P.A. (IT) 2025-02-13 US claimed
US-12156413-B2 Organic solar cells and methods of making the same UNIV NEW YORK (US) 2024-11-26 US claimed
US-20240343739-A1 TWO DIMENSIONAL BENZO[4,5]IMIDAZO[2,1-A]ISOINDOLEINCORPORATED NON-FULLERENE ELECTRON ACCEPTORS FOR ORGANIC PHOTOVOLTAIC DEVICES NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2024-10-17 US claimed
EP-4444723-A1 DIARYLOXYBENZOHETERODIAZOLE COMPOUNDS DISUBSTITUTED WITH THIENOTHIOPHENE GROUPS ENI S.p.A. (IT) 2024-10-16 EP claimed
CN-118284614-A Diaryloxybenzobisoxazole compounds disubstituted with thienothiophene groups 埃尼股份公司 2024-07-02 CN claimed
EP-3563436-B1 HOLE TRANSPORTING MATERIAL AND PHOTOVOLTAIC DEVICE THAT USES IT ENI SPA (IT) 2024-06-26 EP claimed
CN-104448253-A Aromatic alkyne copolymer based on benzo[1,2-b:4,5-b']dithiophene and preparation method thereof UNIV SHANGHAI 2015-03-25 CN claimed
US-20150060774-A1 IMAGE SENSORS WITH ORGANIC PHOTODIODES AND METHODS FOR FORMING THE SAME TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) 2015-03-05 US claimed
US-20150060775-A1 ORGANIC PHOTO DIODE WITH DUAL ELECTRON BLOCKING LAYERS TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) 2015-03-05 US claimed
US-20130334520-A1 GERMOLE CONTAINING CONJUGATED MOLECULES AND POLYMERS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2013-12-19 US claimed
EP-1964842-B1 5H-THIENO [3,4-c]PYRROLE-4, 6-DIONE DERIVATIVES AGAINST CELL RELEASING TUMOR NECROSIS FACTOR TIAN JIN HEMAY BIO TECH CO LTD (CN) 2012-09-12 EP claimed
WO-2012118728-A2 GERMOLE CONTAINING CONJUGATED MOLECULES AND POLYMERS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2012-09-07 WO claimed
US-20080176900-A1 5H-THIOENO(3,4-c)PYRROLE-4,6-DIONE DERIVATIVES AND THEIR USE AS TUMOR NECROSIS FACTOR INHIBITORS TIANJIN HEMAY BIO-TECH CO., LTD. (CN) 2008-07-24 US claimed
EP-1042315-B1 CYCLIC IMIDE-SUBSTITUTED PYRIDYLALKANE, ALKENE, AND ALKINE CARBOXAMIDES USEFUL AS CYTOSTATIC AND IMMUNOSUPPRESSIVE AGENTS KLINGE CO CHEM PHARM FAB (DE) 2004-04-14 EP claimed
EP-1042315-A1 CYCLIC IMIDE-SUBSTITUTED PYRIDYLALKANE, ALKENE, AND ALKINE CARBOXAMIDES USEFUL AS CYTOSTATIC AND IMMUNOSUPPRESSIVE AGENTS Klinge Pharma GmbH (DE) 2000-10-11 EP claimed
WO-1999031087-A1 CYCLIC IMIDE-SUBSTITUTED PYRIDYLALKANE, ALKENE AND ALKINE CARBOXAMIDES USEFUL AS CYTOSTATIC AND IMMUNOSUPPRESSIVE AGENTS KLINGE PHARMA GMBH (DE) 1999-06-24 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240343739-A1 TWO DIMENSIONAL BENZO[4,5]IMIDAZO[2,1-A]ISOINDOLEINCORPORATED NON-FULLERENE ELECTRON ACCEPTORS FOR ORGANIC PHOTOVOLTAIC DEVICES WASF2, OPRM1, VDAC2 GSK3B 4444/4885CASP7 4091/4885CASP3 3788/4885
US-20080176900-A1 5H-THIOENO(3,4-c)PYRROLE-4,6-DIONE DERIVATIVES AND THEIR USE AS TUMOR NECROSIS FACTOR INHIBITORS TNF, TNFRSF1A, CD40 GSK3B 2996/4885CASP7 333/4885CASP3 1095/4885
US-20250051352-A1 DIARYLOXYBENZOHETERODIAZOLE COMPOUNDS DISUBSTITUTED WITH THIENOTHIOPHENE GROUPS SLC9A5, SLC7A5, SLC39A3 GSK3B 3030/4885CASP7 3330/4885CASP3 2702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.