Piperamide

Piperamide

SCHEMBL635749

CC(=O)Nc1ccc(N2CCN(CCCN(C)C)CC2)cc1

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HTR7 P34969 2/20 0.61
▸ MEN1 O00255 3/20 0.57
▸ KMT2A Q03164 3/20 0.57
▸ MAPT P10636 2/20 0.57
▸ GAA P10253 2/20 0.57
▸ KDM4E B2RXH2 1/20 0.57
▸ ALDH1A1 P00352 1/20 0.57
▸ CYP1A2 P05177 1/20 0.56
▸ CYP3A4 P08684 1/20 0.56
▸ CYP2C19 P33261 1/20 0.56
▸ GFER P55789 1/20 0.56
▸ CACNA1G O43497 1/20 0.54
▸ HTT P42858 1/20 0.54
▸ DRD2 P14416 3/20 0.51
▸ DRD4 P21917 1/20 0.51
▸ HTR1A P08908 2/20 0.50
▸ CHRNA10 Q9GZZ6 1/20 0.50
▸ CHRNA9 Q9UGM1 1/20 0.50
▸ LMNA P02545 1/20 0.50
▸ RXFP1 Q9HBX9 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10401572 0.78 MAPT (0.61) MEN1KMT2AMAPTGAAKDM4E
SCHEMBL13912 0.77 KMT2A (0.75) MEN1KMT2AMAPTGAAKDM4E
Hydrochloric Acid SCHEMBL10401971 0.77 MAPT (0.60) MEN1KMT2AMAPTGAAKDM4E
SCHEMBL4499003 0.76 KDM4E (0.58) HTR7KMT2AMAPTGAAKDM4E
SCHEMBL4514129 0.76 DRD2 (0.58) MEN1KMT2AMAPTGAAKDM4E
SCHEMBL9382745 0.74 MAPT (0.75) MEN1KMT2AMAPTGAAKDM4E
SCHEMBL975489 0.74 MAPT (1.00) MEN1KMT2AMAPTGAAKDM4E
SCHEMBL4507337 0.74 SIRT6 (0.60) HTR7KMT2AMAPTALDH1A1HTR1A
SCHEMBL9742938 0.74 MEN1 (0.70) MEN1KMT2AMAPTGAAKDM4E
SCHEMBL15807633 0.74 MAPT (0.69) MEN1KMT2AMAPTGAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8268352-B2 Modified release composition for highly soluble drugs TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-18 — — US claimed
US-8263125-B2 Dosage form for high dose-high solubility active ingredients that provides for immediate release and modified release of the active ingredients TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-11 — — US claimed
US-20060024365-A1 Novel dosage form VAYA NAVIN 2006-02-02 — — US claimed
US-20060018933-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 — — US claimed
US-20060018934-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 — — US claimed
US-12605333-B2 Modified release drug powder composition comprising gastro-retentive raft forming systems having trigger pulse drug release TRIS PHARMA, INC. (US) 2026-04-21 — — US disclosed
US-20260096986-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING A FLOATING INTERPENETRATING POLYMER NETWORK FORMING SYSTEM TRIS PHARMA INC (US) 2026-04-09 — — US disclosed
EP-4706683-A2 CHEWABLE FORMULATIONS Elanco Tiergesundheit AG (CH) 2026-03-11 — — EP disclosed
US-20260034059-A1 ORAL FILM COMPOSITIONS AND DOSAGE FORMS HAVING PRECISE ACTIVE DISSOLUTION PROFILES AQUESTIVE THERAPEUTICS, INC. (US) 2026-02-05 — — US disclosed
US-12514818-B2 Pharmaceutical compositions comprising a floating interpenetrating polymer network forming system TRIS PHARMA, INC. (US) 2026-01-06 — — US disclosed
US-12465564-B2 Oral and nasal compositions and methods of treatment AQUESTIVE THERAPEUTICS, INC. (US) 2025-11-11 — — US disclosed
US-20250339367-A1 ORAL FILM COMPOSITIONS AND DOSAGE FORMS HAVING PRECISE ACTIVE DISSOLUTION PROFILES AQUESTIVE THERAPEUTICS, INC. (US) 2025-11-06 — — US disclosed
US-20030059471-A1 Oral delivery formulation COMPTON BRUCE JON (US) 2003-03-27 — — US disclosed
US-20020010208-A1 Targeting a pharmaceutical agent to a noncentral nervous system tissue by administering a covalent conjugate of the drug and cis-docosahexanoic acid LUITPOLD PHARMACEUTICALS, INC. 2002-01-24 — — US disclosed
US-20010002404-A1 Fatty acid-pharmaceutical agent conjugates LUITPOLD PHARMACEUTICALS, INC. 2001-05-31 — — US disclosed
WO-2000040604-A2 METHODS AND COMPOSITIONS FOR MODULATING CYTOKINE RELEASE BY αEβ7-EXPRESSING CELLS THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2000-07-13 — — WO disclosed
WO-1999030690-A1 ORAL DELIVERY FORMULATION AXIA THERAPEUTICS, INC. (US) 1999-06-24 — — WO disclosed
EP-0909183-A2 DHA-PHARMACEUTICAL AGENT CONJUGATES Neuromedica, Inc. (US) 1999-04-21 — — EP disclosed
US-5795909-A ANTICARCINOGENIC AND ANTITUMOR AGENTS; BREAST, COLON, OVARIANCANCERS NEUROMEDICA, INC. (US) 1998-08-18 — — US disclosed
WO-1997044063-A2 DHA-PHARMACEUTICAL AGENT CONJUGATES NEUROMEDICA, INC. (US) 1997-11-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020010208-A1 Targeting a pharmaceutical agent to a noncentral nervous system tissue by administering a covalent conjugate of the drug and cis-docosahexanoic acid FABP7, FADS2, ALOX5 HTR7 1912/4885MEN1 3392/4885KMT2A 4304/4885
US-20260096986-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING A FLOATING INTERPENETRATING POLYMER NETWORK FORMING SYSTEM SI, FABP2, FABP6 HTR7 327/4885MEN1 3578/4885KMT2A 4594/4885
US-12605333-B2 Modified release drug powder composition comprising gastro-retentive raft forming systems having trigger pulse drug release SI, GRPR, FABP2 HTR7 447/4885MEN1 4654/4885KMT2A 3577/4885
US-20010002404-A1 Fatty acid-pharmaceutical agent conjugates FABP7, FFAR2, FFAR4 HTR7 1036/4885MEN1 3479/4885KMT2A 3261/4885
US-20260034059-A1 ORAL FILM COMPOSITIONS AND DOSAGE FORMS HAVING PRECISE ACTIVE DISSOLUTION PROFILES SORD, SLC6A13, CACNA1A HTR7 814/4885MEN1 2827/4885KMT2A 1839/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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