Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 11/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6713832 | 0.85 | MAPT (0.49) | SIRT2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL6351360 | 0.84 | METAP2 (0.55) | SIRT2MAPTKDM4EHTTMAPK1 | |
| SCHEMBL6711828 | 0.82 | SLC10A6 (0.52) | SIRT2MAPTKDM4EHTTMAPK1 | |
| SCHEMBL6710371 | 0.82 | MAPT (0.46) | SIRT2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL15838803 | 0.81 | SIRT2 (0.73) | SIRT2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL6358696 | 0.80 | SIRT2 (0.63) | SIRT2KDM4EALDH1A1HTTMAPK1 | |
| SCHEMBL15953505 | 0.78 | SIRT2 (0.74) | SIRT2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL6710361 | 0.78 | GPR35 (0.48) | SIRT2MAPTKDM4EHTTMAPK1 | |
| SCHEMBL7063908 | 0.76 | METAP2 (0.50) | SIRT2KDM4EHTTMAPK1 | |
| SCHEMBL6707819 | 0.76 | KDM4E (0.46) | SIRT2MAPTKDM4EHTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | SIRT2 2621/4885MAPT 4754/4885KDM4E 1582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.