Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 15/20 | 0.69 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.67 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.67 |
| ▸ | CTSS | P25774 | 6/20 | 0.66 |
| ▸ | CTSL | P07711 | 2/20 | 0.66 |
| ▸ | CTSB | P07858 | 1/20 | 0.66 |
| ▸ | CA5A | P35218 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14067668 | 0.89 | CTSK (0.77) | CTSKCAPN1CAPN2CTSSCTSL | |
| SCHEMBL6365264 | 0.88 | CTSS (0.53) | CTSKCAPN1CAPN2CTSSCTSL | |
| SCHEMBL6360713 | 0.87 | SMN1; SMN2 (0.56) | CTSKCAPN1CAPN2CTSSCTSL | |
| SCHEMBL29052549 | 0.87 | CTSK (0.77) | CTSKCAPN1CAPN2CTSSCTSL | |
| SCHEMBL29052552 | 0.87 | CTSK (0.77) | CTSKCAPN1CAPN2CTSSCTSL | |
| SCHEMBL9115066 | 0.85 | CAPN1 (0.80) | CTSKCAPN1CAPN2CTSSCTSL | |
| SCHEMBL6361024 | 0.85 | SIRT2 (0.62) | CTSSCTSL | |
| SCHEMBL6361021 | 0.85 | SIRT2 (0.62) | CTSSCTSL | |
| SCHEMBL6358711 | 0.84 | CTSL (0.65) | CTSKCAPN1CAPN2CTSSCTSL | |
| SCHEMBL8750916 | 0.83 | CTSL (0.62) | CTSKCAPN1CAPN2CTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6858591-B2 | Antibiotic AA 896 analogs | WYETH HOLDINGS CORPORATION (US) | 2005-02-22 | — | — | US | disclosed |
| US-20030087874-A1 | 2-amino-3-hydroxy-3-uridyl-propanoic acid ester derivatives | AMERICAN CYANAMID COMPANY | 2003-05-08 | — | — | US | disclosed |
| WO-2002086139-A1 | ANTIBIOTIC AA 896 ANALOGS | WYETH HOLDINGS CORPORATION (US) | 2002-10-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030087874-A1 | 2-amino-3-hydroxy-3-uridyl-propanoic acid ester derivatives | UMPS, METTL3, FPR3 | CTSK 4244/4885CAPN1 1778/4885CAPN2 2144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.