Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CTSL | P07711 | 2/20 | 0.55 |
| ▸ | CTSS | P25774 | 2/20 | 0.55 |
| ▸ | BCHE | P06276 | 2/20 | 0.54 |
| ▸ | ACHE | P22303 | 2/20 | 0.54 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.54 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.54 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.54 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.54 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.53 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.53 |
| ▸ | CTSK | P43235 | 2/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 7/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 6/20 | 0.52 |
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6365264 | 0.93 | CTSS (0.53) | SMN1; SMN2CTSLCTSSCAPN1CAPN2 | |
| SCHEMBL6358735 | 0.87 | CTSK (0.69) | CTSLCTSSCAPN1CAPN2CTSK | |
| SCHEMBL22034396 | 0.87 | NMBR (0.63) | CTSLCTSSCAPN1CAPN2CTSK | |
| SCHEMBL22034395 | 0.87 | NMBR (0.63) | CTSLCTSSCAPN1CAPN2CTSK | |
| SCHEMBL6361024 | 0.87 | SIRT2 (0.62) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL6361021 | 0.87 | SIRT2 (0.62) | CTSLCTSSSIRT2SIRT1SIRT3 | |
| SCHEMBL18758793 | 0.84 | CTSS (0.55) | SMN1; SMN2CTSLCTSSBCHEACHE | |
| SCHEMBL8750916 | 0.83 | CTSL (0.62) | CTSLCTSSCAPN1CAPN2CTSK | |
| SCHEMBL11513551 | 0.83 | BCHE (0.60) | SMN1; SMN2CTSLCTSSBCHEACHE | |
| SCHEMBL11513546 | 0.83 | BCHE (0.60) | SMN1; SMN2CTSLCTSSBCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6858591-B2 | Antibiotic AA 896 analogs | WYETH HOLDINGS CORPORATION (US) | 2005-02-22 | — | — | US | disclosed |
| US-20030087874-A1 | 2-amino-3-hydroxy-3-uridyl-propanoic acid ester derivatives | AMERICAN CYANAMID COMPANY | 2003-05-08 | — | — | US | disclosed |
| WO-2002086139-A1 | ANTIBIOTIC AA 896 ANALOGS | WYETH HOLDINGS CORPORATION (US) | 2002-10-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030087874-A1 | 2-amino-3-hydroxy-3-uridyl-propanoic acid ester derivatives | UMPS, METTL3, FPR3 | SMN1; SMN2 2904/4885CTSL 2129/4885CTSS 3983/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.