Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 18/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 15/20 | 0.49 |
| ▸ | SIRT3 | Q9NTG7 | 12/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6360378 | 1.00 | SIRT2 (0.49) | SIRT2SIRT1SIRT3MEN1ALDH1A1 | |
| SCHEMBL6360549 | 0.86 | SIRT2 (0.48) | SIRT2SIRT1SIRT3MEN1ALDH1A1 | |
| SCHEMBL6360553 | 0.86 | SIRT2 (0.48) | SIRT2SIRT1SIRT3MEN1ALDH1A1 | |
| SCHEMBL7572602 | 0.83 | SIRT2 (0.49) | SIRT2SIRT1SIRT3CTSLCTSB | |
| SCHEMBL6358711 | 0.82 | CTSL (0.65) | MEN1KMT2ACTSLCTSBCTSS | |
| SCHEMBL6361542 | 0.80 | CTSL (0.54) | MEN1KMT2ACTSLCTSBCTSS | |
| SCHEMBL8199768 | 0.78 | CTSL (0.66) | SIRT2SIRT1MEN1KMT2ACTSL | |
| SCHEMBL7348318 | 0.77 | CA2 (0.61) | SIRT2SIRT1SIRT3MEN1ALDH1A1 | |
| SCHEMBL13610345 | 0.77 | CA2 (0.61) | SIRT2SIRT1SIRT3MEN1ALDH1A1 | |
| SCHEMBL6427219 | 0.77 | CA2 (0.61) | SIRT2SIRT1SIRT3MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6858591-B2 | Antibiotic AA 896 analogs | WYETH HOLDINGS CORPORATION (US) | 2005-02-22 | — | — | US | disclosed |
| US-20030087874-A1 | 2-amino-3-hydroxy-3-uridyl-propanoic acid ester derivatives | AMERICAN CYANAMID COMPANY | 2003-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030087874-A1 | 2-amino-3-hydroxy-3-uridyl-propanoic acid ester derivatives | UMPS, METTL3, FPR3 | SIRT2 3523/4885SIRT1 3835/4885SIRT3 3214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.