SCHEMBL6369470

SCHEMBL6369470

C1=NC=NCN1c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
CYP3A4 P08684 1/20 0.32
MAPT P10636 2/20 0.32
NPSR1 Q6W5P4 1/20 0.32
KDM4E B2RXH2 1/20 0.31
SIGMAR1 Q99720 2/20 0.31
LMNA P02545 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6654238 0.84 LTA4H (0.41) SMN1; SMN2LMNAMEN1KMT2A
SCHEMBL27562939 0.72 MAPT (0.32) MAPTNPSR1KDM4ELMNA
SCHEMBL2362320 0.67 MAPT (0.35) HPGDNPC1RAB9ASMN1; SMN2CYP3A4
SCHEMBL2677295 0.67 HPGD (0.38) HPGDNPC1RAB9ASMN1; SMN2CYP3A4
SCHEMBL28274802 0.67 AR (0.41)
SCHEMBL574986 0.65 NPSR1 (0.38) HPGDNPC1RAB9ASMN1; SMN2CYP3A4
SCHEMBL6272216 0.65 SIGMAR1 (0.41) HPGDNPC1RAB9ASMN1; SMN2CYP3A4
SCHEMBL105023 0.65 SIGMAR1 (0.41) HPGDNPC1RAB9ASMN1; SMN2CYP3A4
SCHEMBL8756913 0.65 HPGD (0.40) HPGDNPC1RAB9ASMN1; SMN2CYP3A4
SCHEMBL28053371 0.64 NPC1 (0.36) HPGDNPC1RAB9ASMN1; SMN2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3369728-B1 THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL AND APPLICATION THEREOF IN ORGANIC ELECTROLUMINESCENT DEVICE KUNSHAN GOVISIONOX OPTOELECTRONICS CO LTD (CN) 2020-12-23 EP claimed
US-20190074447-A1 THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL AND APPLICATION THEREOF IN ORGANIC ELECTROLUMINESCENCE DEVICE KUNSHAN GO-VISIONOX OPTO-ELECTRONICS CO., LTD. (CN) 2019-03-07 US claimed
US-20050123906-A1 Protein modulation NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2005-06-09 US claimed
EP-0504290-B1 INHIBITORS OF PNEUMOCYSTIS CARINII DIHYDROFOLATE REDUCTASE CHIRON CORP (US) 1997-01-22 EP claimed
EP-0504290-A4 INHIBITORS OF PNEUMOCYSTIS CARINII DIHYDROFOLATE REDUCTASE 1993-03-24 EP claimed
EP-0504290-A1 INHIBITORS OF PNEUMOCYSTIS CARINII DIHYDROFOLATE REDUCTASE. PROTOS CORP (US) 1992-09-23 EP claimed
WO-1991008667-A1 INHIBITORS OF PNEUMOCYSTIS CARINII DIHYDROFOLATE REDUCTASE PROTOS CORPORATION (US) 1991-06-27 WO claimed
WO-1991008668-A1 INHIBITORS OF PNEUMOCYSTIS CARINII DIHYDROFOLATE REDUCTASE PROTOS CORPORATION (US) 1991-06-27 WO claimed
CN-114276273-B Organic electroluminescent material based on tetraphenylhydrazine derivative and electronic device thereof 维思普新材料(苏州)有限公司 2024-06-21 CN disclosed
CN-114573499-B 9, 9-Dicarbazole derivative, preparation method thereof and application thereof in luminescence 维思普新材料(苏州)有限公司 2024-05-10 CN disclosed
CN-117402130-A 1,3, 4-triaryl substituted dibenzofuran compound and light-emitting device thereof 维思普新材料(苏州)有限公司 2024-01-16 CN disclosed
CN-116655666-A Boron-containing organic compound and light-emitting device 中国科学技术大学 2023-08-29 CN disclosed
CN-116217529-B Fluorene furan compound and light-emitting device thereof 维思普新材料(苏州)有限公司 2023-07-28 CN disclosed
CN-116217529-A Fluorene furan compound and light-emitting device thereof 维思普新材料(苏州)有限公司 2023-06-06 CN disclosed
EP-0504290-A1 INHIBITORS OF PNEUMOCYSTIS CARINII DIHYDROFOLATE REDUCTASE. PROTOS CORP (US) 1992-09-23 EP disclosed
WO-1991008667-A1 INHIBITORS OF PNEUMOCYSTIS CARINII DIHYDROFOLATE REDUCTASE PROTOS CORPORATION (US) 1991-06-27 WO disclosed
WO-1991008667-A1 INHIBITORS OF PNEUMOCYSTIS CARINII DIHYDROFOLATE REDUCTASE PROTOS CORPORATION (US) 1991-06-27 WO disclosed
WO-1991008668-A1 INHIBITORS OF PNEUMOCYSTIS CARINII DIHYDROFOLATE REDUCTASE PROTOS CORPORATION (US) 1991-06-27 WO disclosed
WO-1991008668-A1 INHIBITORS OF PNEUMOCYSTIS CARINII DIHYDROFOLATE REDUCTASE PROTOS CORPORATION (US) 1991-06-27 WO disclosed
EP-0339555-A2 Water soluble preparations of coccidiostatics HOECHST AKTIENGESELLSCHAFT (DE) 1989-11-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190074447-A1 THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL AND APPLICATION THEREOF IN ORGANIC ELECTROLUMINESCENCE DEVICE KCNH1, KCNH2, KCNH3 HPGD 4501/4885NPC1 3294/4885RAB9A 1332/4885
US-20050123906-A1 Protein modulation MAVS, PPP4R3A, PPP1R10 HPGD 3801/4885NPC1 2184/4885RAB9A 2402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.