Emate

Emate

SCHEMBL305660

C[C@]12CC[C@@H]3c4ccc(OS(N)(=O)=O)cc4CC[C@H]3[C@@H]1CCC2=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STS P08842 16/20 1.00
CA2 P00918 4/20 1.00
CA1 P00915 3/20 1.00
CA9 Q16790 3/20 1.00
ESR1 P03372 2/20 1.00
ESR2 Q92731 2/20 1.00
CA4 P22748 1/20 1.00
CA6 P23280 1/20 1.00
ABCC4 O15439 1/20 0.80
CYP2C9 P11712 1/20 0.80
ABCC1 P33527 1/20 0.80
SLCO1B1 Q9Y6L6 1/20 0.80
KDM4E B2RXH2 1/20 0.80
LMNA P02545 2/20 0.76
MAPT P10636 2/20 0.76
HSD17B1 P14061 2/20 0.76
RECQL P46063 1/20 0.76
SMN1; SMN2 Q16637 1/20 0.76
CYP3A4 P08684 2/20 0.73
CA5A P35218 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Emate SCHEMBL14548146 1.00 STS (1.00) STSCA2CA1CA9ESR1
Emate SCHEMBL29406834 1.00 STS (1.00) STSCA2CA1CA9ESR1
Emate SCHEMBL10062721 1.00 STS (1.00) STSCA2CA1CA9ESR1
Emate SCHEMBL6370815 1.00 STS (1.00) STSCA2CA1CA9ESR1
SCHEMBL21067318 0.91 STS (0.84) STSCA2CA1CA9ESR1
Emate SCHEMBL7164522 0.91 STS (0.86) STSCA2CA1CA9ESR1
SCHEMBL17531381 0.90 STS (0.82) STSCA2CA1CA9ESR1
SCHEMBL8034430 0.90 STS (0.82) STSCA2CA1CA9ESR1
Estrone Sulfuric Acid SCHEMBL2296097 0.89 KDM4E (0.96) STSCA2CA1CA9ESR1
Estrone Sulfuric Acid SCHEMBL22846 0.89 STS (1.00) STSCA2CA1CA9ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 548 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025079965-A1 COMPOSITION FOR PREVENTION OR TREATMENT OF PERIODONTAL DISEASES 주식회사 넥시온바이오텍 2025-04-17 WO claimed
US-20240082208-A1 ANTIVIRAL PHARMACEUTICAL COMPOSITION COMPRISING STEROID SULFATASE INHIBITOR NEXYON BIOTECH CO., LTD. (KR) 2024-03-14 US claimed
US-20230405020-A1 SULFATED C19 STEROID HORMONES TO TREAT AND/OR PREVENT PROTEOTOXICITY IN PROTEIN-AGGREGATION DISEASES UNIVERSIDAD PABLO DE OLAVIDE (ES) 2023-12-21 US claimed
EP-4275683-A1 ANTIVIRAL PHARMACEUTICAL COMPOSITION COMPRISING STEROID SULFATASE INHIBITOR Industry-Academic Cooperation Foundation, Yonsei University (KR) 2023-11-15 EP claimed
CN-116916912-A Protein toxicity of sulfated C19 steroid hormone for treatment and/or prevention of protein aggregation disease 帕布罗·德奥拉韦德大学 2023-10-20 CN claimed
EP-4232021-A1 SULFATED C19 STEROID HORMONES TO TREAT AND/OR PREVENT PROTEOTOXICITY IN PROTEIN-AGGREGATION DISEASES Universidad Pablo de Olavide (ES) 2023-08-30 EP claimed
WO-2022149929-A1 ANTIVIRAL PHARMACEUTICAL COMPOSITION COMPRISING STEROID SULFATASE INHIBITOR 연세대학교 산학협력단 2022-07-14 WO claimed
WO-2022090247-A1 SULFATED C19 STEROID HORMONES TO TREAT AND/OR PREVENT PROTEOTOXICITY IN PROTEIN-AGGREGATION DISEASES UNIVERSIDAD PABLO DE OLAVIDE OTRI (ES) 2022-05-05 WO claimed
EP-3939584-A1 COMPOSITION FOR PREVENTING OR TREATING OBESITY OR LIPID-RELATED METABOLIC DISORDERS Nexyon Biotech Co., Ltd. (KR) 2022-01-19 EP claimed
US-20210393581-A1 Composition for Preventing or Treating Obesity or Lipid-Related Metabolic Disorders NEXYON BIOTECH CO., LTD. (KR) 2021-12-23 US claimed
EP-0982032-A2 Use of a ring system compound comprising a sulphamic acid ester group for the manufacture of medicaments for the control of oestrogen production Sterix Limited (GB) 2000-03-01 EP claimed
US-6013642-A ANTIINFLAMMATORY AGENT FOULKES ROLAND (GB) 2000-01-11 US claimed
EP-0928609-A2 Use of sulphamate derivatives as steroid sulphatase inhibitors IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE (GB) 1999-07-14 EP claimed
EP-0921130-A2 Steroid sulphatase inhibitors IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY & MEDICINE (GB) 1999-06-09 EP claimed
US-5891620-A Steroid sulfatase assay IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE (GB) 1999-04-06 US claimed
EP-0791073-A2 ASSAY IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY & MEDICINE (GB) 1997-08-27 EP claimed
US-5616574-A ANTITUMOR AGENTS FOR BREAST CANCER IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE (GB) 1997-04-01 US claimed
WO-1996015257-A2 STEROID SULFATASE ASSAY IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE (GB) 1996-05-23 WO claimed
EP-0641355-A1 STEROID SULPHATASE INHIBITORS IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE (GB) 1995-03-08 EP claimed
WO-1993005064-A1 STEROID SULPHATASE INHIBITORS IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE (GB) 1993-03-18 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210393581-A1 Composition for Preventing or Treating Obesity or Lipid-Related Metabolic Disorders LIPC, FABP4, PNLIP STS 137/4885CA2 2913/4885CA1 3963/4885
US-20230405020-A1 SULFATED C19 STEROID HORMONES TO TREAT AND/OR PREVENT PROTEOTOXICITY IN PROTEIN-AGGREGATION DISEASES SERPINA6, HTT, PSMG3 STS 200/4885CA2 3789/4885CA1 1833/4885
US-20240082208-A1 ANTIVIRAL PHARMACEUTICAL COMPOSITION COMPRISING STEROID SULFATASE INHIBITOR STS, SULT2A1, CYP21A2 STS 1/4885CA2 2843/4885CA1 3153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.