SCHEMBL638147

SCHEMBL638147

[CH]=Cc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.59
FBP1 P09467 2/20 0.57
NPC1 O15118 1/20 0.53
MAPT P10636 1/20 0.53
RAB9A P51151 1/20 0.53
PTGS2 P35354 4/20 0.50
ALDH1A1 P00352 2/20 0.50
PTGS1 P23219 2/20 0.50
ACHE P22303 1/20 0.50
HSD17B10 Q99714 1/20 0.50
CYP19A1 P11511 1/20 0.50
LMNA P02545 1/20 0.48
METAP1 P53582 1/20 0.47
GRIN2D O15399 1/20 0.47
GRIN3B O60391 1/20 0.47
GRIN1 Q05586 1/20 0.47
GRIN2A Q12879 1/20 0.47
GRIN2B Q13224 1/20 0.47
GRIN2C Q14957 1/20 0.47
GRIN3A Q8TCU5 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9170804 0.80 APP (0.78) APPFBP1NPC1MAPTRAB9A
SCHEMBL9170800 0.80 APP (0.78) APPFBP1NPC1MAPTRAB9A
SCHEMBL439935 0.80 APP (0.64) APPFBP1NPC1MAPTRAB9A
SCHEMBL458177 0.80 APP (0.78) APPFBP1NPC1MAPTRAB9A
SCHEMBL14947048 0.80 APP (0.78) APPFBP1NPC1MAPTRAB9A
SCHEMBL458178 0.80 APP (0.78) APPFBP1NPC1MAPTRAB9A
SCHEMBL22567 0.79 ALDH1A1 (0.72) APPALDH1A1ACHEHSD17B10LMNA
SCHEMBL27909482 0.79 ALDH1A1 (0.72) APPALDH1A1ACHEHSD17B10LMNA
SCHEMBL8731305 0.78 APP (0.61) APPFBP1NPC1MAPTRAB9A
SCHEMBL1157 0.78 APP (0.61) APPFBP1NPC1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 194 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112321401-B Method for preparing 2-hydroxyethyl phenyl ketone by catalytic oxidation of heterochroman 西安石油大学 2023-04-28 CN claimed
CN-114195687-A Beta-chloro tetra-substituted alkenyl sulfone compound and synthetic method thereof 华南理工大学 2022-03-18 CN claimed
CN-113214342-A 23-hydroxy betulinic acid 3-site modified derivative, preparation method and application 中国药科大学 2021-08-06 CN claimed
CN-110330475-B Preparation method of alpha, alpha-disubstituted isochroman compounds 西安石油大学 2021-02-12 CN claimed
CN-112321402-A Method for preparing 2-hydroxyethyl phenyl ketone by coupling two components 西安石油大学 2021-02-05 CN claimed
CN-110694652-A Method for generating ester compound by catalytic oxidation of ether compound with visible light excited silver iodide and bismuth vanadate composite material 潍坊医学院 2020-01-17 CN claimed
US-10065926-B2 Use of substituted dihydrooxindolylsulfonamides, or the salts thereof, for increasing the stress tolerance of plants BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-09-04 US claimed
CN-107501380-A 23 hydroxyl radical white birck acid 23 modified derivative, preparation method and the usages 中国药科大学 2017-12-22 CN claimed
EP-3051946-B1 USE OF SUBSTITUTED DIHYDROOXINDOLYLSULFONAMIDES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE IN PLANTS BAYER CROPSCIENCE AG (DE) 2017-11-29 EP claimed
US-20160237035-A1 USE OF SUBSTITUTED DIHYDROOXINDOLYLSULFONAMIDES, OR THE SALTS THEREOF, FOR INCREASING THE STRESS TOLERANCE OF PLANTS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-08-18 US claimed
US-5073501-A Adding complexing chromogenic crypt compounds TECHNICON INSTRUMENTS CORPORATION (US) 1991-12-17 US claimed
US-5011924-A Measurement Of Ions TECHNICON INSTRUMENTS CORPORATION (US) 1991-04-30 US claimed
US-4994395-A Determination of potassium cations TECHNICON INSTRUMENTS CORPORATION (US) 1991-02-19 US claimed
US-4992381-A Method of detecting electrolytes in an aqueous test sample using chromogenic hemispherands and test device therefor TECHNICON INSTRUMENTS CORPORATION (US) 1991-02-12 US claimed
US-4859606-A Method for detecting cations in a test sample utilizing chromogenic cryptahemispherands TECHNICON INSTRUMENTS CORPORATION (US) 1989-08-22 US claimed
US-4808539-A CRYPT COMPOUNDS TECHNICON INSTRUMENTS CORPORATION (US) 1989-02-28 US claimed
EP-0287330-A2 Chromogenic hemispherands useful for detecting electrolytes Bayer Corporation (US) 1988-10-19 EP claimed
EP-0287327-A2 Compounds for determining cations Bayer Corporation (US) 1988-10-19 EP claimed
EP-0287329-A2 Chromogenic cryptahemispherands useful in detecting electrolytes Bayer Corporation (US) 1988-10-19 EP claimed
US-4198406-A Carbamoyl heterocyclicthio cephalosporins and pharmaceutical compositions formulated therewith BEECHAM GROUP LIMITED (GB) 1980-04-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10065926-B2 Use of substituted dihydrooxindolylsulfonamides, or the salts thereof, for increasing the stress tolerance of plants SQOR, DHPS, QDPR APP 4398/4885FBP1 353/4885NPC1 3858/4885
US-20160237035-A1 USE OF SUBSTITUTED DIHYDROOXINDOLYLSULFONAMIDES, OR THE SALTS THEREOF, FOR INCREASING THE STRESS TOLERANCE OF PLANTS SQOR, DHPS, QDPR APP 4398/4885FBP1 353/4885NPC1 3858/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.