Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GLS | O94925 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CASP2 | P42575 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27528908 | 0.89 | KMT2A (0.44) | ALDH1A1CYP3A4TSHRHPGDKMT2A | |
| SCHEMBL17221835 | 0.86 | ALDH1A1 (0.41) | ALDH1A1CYP3A4TSHRHSD17B10MAPK1 | |
| SCHEMBL4014931 | 0.85 | ALDH1A1 (0.62) | ALDH1A1CYP3A4TSHRHSD17B10HPGD | |
| SCHEMBL12571904 | 0.84 | CYP1A2 (0.44) | ALDH1A1CYP3A4TSHRHPGDMAPK1 | |
| SCHEMBL24091673 | 0.84 | RAB9A (0.44) | ALDH1A1CYP3A4TSHRHPGDKMT2A | |
| SCHEMBL29473539 | 0.83 | ALDH1A1 (0.53) | ALDH1A1CYP3A4TSHRHSD17B10HPGD | |
| SCHEMBL4013821 | 0.83 | ALDH1A1 (0.53) | ALDH1A1CYP3A4TSHRHSD17B10HPGD | |
| SCHEMBL19031592 | 0.83 | KDM4E (0.44) | ALDH1A1CYP3A4TSHRKDM4EGAA | |
| SCHEMBL19031584 | 0.83 | ALDH1A1 (0.39) | ALDH1A1CYP3A4HPGDKMT2ASMN1; SMN2 | |
| SCHEMBL19031506 | 0.83 | CYP2D6 (0.42) | ALDH1A1CYP3A4TSHRHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050006246-A1 | Nitrogen atom transfer | YUDIN ANDREI K (CA) | 2005-01-13 | — | — | US | claimed |
| WO-2003010361-A2 | NITROGEN ATOM TRANSFER | YLEKTRA INC. (CA) | 2003-02-06 | — | — | WO | claimed |
| EP-3440051-B1 | NEUROPEPTIDE S RECEPTOR (NPSR) AGONISTS | RES TRIANGLE INST (US) | 2024-03-20 | — | — | EP | disclosed |
| US-20210380635-A1 | COMPOSITIONS AND METHODS FOR PROTEIN LABELING, MODIFICATION, ANALYSIS, AND TARGETED DELIVERY | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-12-09 | — | — | US | disclosed |
| US-11186678-B2 | Radical cascade-enabled synthesis of precision polymers with complex main-chain structures | TRUSTEES OF BOSTON COLLEGE (US) | 2021-11-30 | — | — | US | disclosed |
| US-11142546-B2 | Neuropeptide S receptor (NPSR) agonists | RESEARCH TRIANGLE INSTITUTE (US) | 2021-10-12 | — | — | US | disclosed |
| US-20200216610-A1 | RADICAL CASCADE-ENABLED SYNTHESIS OF PRECISION POLYMERS WITH COMPLEX MAIN-CHAIN STRUCTURES | TRUSTEES OF BOSTON COLLEGE (US) | 2020-07-09 | — | — | US | disclosed |
| WO-2019060809-A1 | INHIBITORS OF PSEUDOMONAS AERUGINOSA VIRULENCE | CHANNEL THERAPEUTICS, INC. (US) | 2019-03-28 | — | — | WO | disclosed |
| US-20190092809-A1 | NEUROPEPTIDE S RECEPTOR (NPSR) AGONISTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2019-03-28 | — | — | US | disclosed |
| EP-3440051-A1 | NEUROPEPTIDE S RECEPTOR (NPSR) AGONISTS | Research Triangle Institute (US) | 2019-02-13 | — | — | EP | disclosed |
| WO-2017176461-A1 | NEUROPEPTIDE S RECEPTOR (NPSR) AGONISTS | RESEARCH TRIANGLE INSTITUTE (US) | 2017-10-12 | — | — | WO | disclosed |
| WO-2017109795-A1 | NOVEL COMPOUNDS USEFUL AS POTENTIAL INSECT ANTIFEEDANT AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-06-29 | — | — | WO | disclosed |
| US-9249139-B2 | Indolizinone based derivatives as potential phosphodiesterase 3 (PDE3) inhibitors and a process for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-02-02 | — | — | US | disclosed |
| US-20150045556-A1 | PROCESSES FOR THE PREPARATION OF PERIPHERAL OPIOID ANTAGONIST COMPOUNDS AND INTERMEDIATES THERETO | DOLLE ROLAND E (US) | 2015-02-12 | — | — | US | disclosed |
| WO-2013012871-A1 | PROCESSES FOR THE PREPARATION OF PERIPHERAL OPIOID ANTAGONIST COMPOUNDS AND INTERMEDIATES THERETO | ADOLOR CORPORATION (US) | 2013-01-24 | — | — | WO | disclosed |
| US-20070203224-A1 | SMALL-MOLECULES FOR TREATING CANCER AND ABNORMAL CELL PROLIFERATION DISORDERS | UNIVERSITY OF SOUTHERN CALIFORNIA | 2007-08-30 | — | — | US | disclosed |
| US-20070203224-A1 | SMALL-MOLECULES FOR TREATING CANCER AND ABNORMAL CELL PROLIFERATION DISORDERS | UNIVERSITY OF SOUTHERN CALIFORNIA | 2007-08-30 | — | — | US | disclosed |
| WO-2007081966-A2 | SMALL MOLECULES FOR TREATING CANCER AND ABNORMAL CELL PROLIFERATION DISORDERS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2007-07-19 | — | — | WO | disclosed |
| US-20050006246-A1 | Nitrogen atom transfer | YUDIN ANDREI K (CA) | 2005-01-13 | — | — | US | disclosed |
| WO-2003010361-A2 | NITROGEN ATOM TRANSFER | YLEKTRA INC. (CA) | 2003-02-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150045556-A1 | PROCESSES FOR THE PREPARATION OF PERIPHERAL OPIOID ANTAGONIST COMPOUNDS AND INTERMEDIATES THERETO | OPRK1, OPRM1, OPRD1 | ALDH1A1 2714/4885CYP3A4 137/4885TSHR 985/4885 |
| US-20190092809-A1 | NEUROPEPTIDE S RECEPTOR (NPSR) AGONISTS | NPSR1, GRPR, NPBWR1 | ALDH1A1 4747/4885CYP3A4 3917/4885TSHR 62/4885 |
| US-20210380635-A1 | COMPOSITIONS AND METHODS FOR PROTEIN LABELING, MODIFICATION, ANALYSIS, AND TARGETED DELIVERY | PTMS, SRMS, CHAMP1 | ALDH1A1 3049/4885CYP3A4 3746/4885TSHR 3028/4885 |
| US-11142546-B2 | Neuropeptide S receptor (NPSR) agonists | NPSR1, GRPR, NPBWR1 | ALDH1A1 4747/4885CYP3A4 3917/4885TSHR 62/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.