Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGER | Q15109 | 3/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2814615 | 0.80 | AGER (0.67) | AGERMTNR1AL3MBTL1RAB9AALDH1A1 | |
| SCHEMBL6409269 | 0.77 | S1PR3 (0.48) | L3MBTL1S1PR1S1PR3RAB9AALDH1A1 | |
| SCHEMBL6409920 | 0.75 | ALDH1A1 (0.59) | RAB9AALDH1A1SMN1; SMN2NPC1NPSR1 | |
| SCHEMBL6407336 | 0.73 | EPHX1 (0.63) | L3MBTL1RAB9AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL3370759 | 0.72 | AGER (0.55) | AGERMTNR1AL3MBTL1OPRM1 | |
| SCHEMBL5436734 | 0.71 | AGER (0.55) | AGERMTNR1AL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL5431901 | 0.71 | AGER (0.55) | AGERMTNR1AL3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL6409923 | 0.70 | NPSR1 (0.47) | L3MBTL1S1PR1S1PR3RAB9AALDH1A1 | |
| SCHEMBL6403405 | 0.70 | ADRB2 (0.44) | L3MBTL1RAB9AALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL23175993 | 0.68 | AGER (0.63) | AGERMTNR1AL3MBTL1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | SDS BIOTECH K.K. (JP) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | AHR, ERG28, CYP1A2 | AGER 3522/4885MTNR1A 1101/4885L3MBTL1 607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.