Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6409920 | 0.71 | ALDH1A1 (0.59) | NPSR1SMN1; SMN2LMNARAB9ANPC1 | |
| SCHEMBL8819827 | 0.70 | PKM (0.59) | SMN1; SMN2LMNARAB9ANPC1ALDH1A1 | |
| SCHEMBL6403397 | 0.70 | AGER (0.47) | NPSR1SMN1; SMN2RAB9ANPC1L3MBTL1 | |
| SCHEMBL19750331 | 0.69 | MEN1 (0.64) | NPSR1SMN1; SMN2LMNARAB9ANPC1 | |
| SCHEMBL9001874 | 0.68 | OPRM1 (0.45) | SMN1; SMN2LMNAMEN1KMT2AOPRM1 | |
| SCHEMBL11465189 | 0.68 | NPC1 (0.42) | NPSR1UCHL1USP30RAB9ANPC1 | |
| SCHEMBL24636855 | 0.68 | POLB (0.66) | SMN1; SMN2LMNARAB9ANPC1ALDH1A1 | |
| SCHEMBL554742 | 0.67 | SMN1; SMN2 (0.57) | SMN1; SMN2RAB9AL3MBTL1ALDH1A1TDP1 | |
| SCHEMBL8879575 | 0.67 | SMN1; SMN2 (0.53) | SMN1; SMN2RAB9ANPC1L3MBTL1ALDH1A1 | |
| SCHEMBL9001804 | 0.66 | HSD17B1 (0.49) | SMN1; SMN2LMNARAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | SDS BIOTECH K.K. (JP) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | AHR, ERG28, CYP1A2 | NPSR1 1583/4885SMN1; SMN2 4458/4885LMNA 3019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.