Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 17/20 | 0.55 |
| ▸ | CTSS | P25774 | 10/20 | 0.55 |
| ▸ | CTSB | P07858 | 8/20 | 0.55 |
| ▸ | CTSK | P43235 | 8/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6403855 | 1.00 | CTSL (0.55) | CTSLCTSSCTSBCTSKCYP2D6 | |
| SCHEMBL5800380 | 0.88 | CTSL (0.52) | CTSLCTSSCTSBCTSKCYP2D6 | |
| SCHEMBL6208313 | 0.86 | CTSL (0.53) | CTSLCTSSCTSBCTSK | |
| SCHEMBL6208306 | 0.86 | CTSL (0.53) | CTSLCTSSCTSBCTSK | |
| SCHEMBL6268990 | 0.83 | CTSK (0.49) | CTSLCTSSCTSBCTSK | |
| SCHEMBL6268987 | 0.83 | CTSK (0.49) | CTSLCTSSCTSBCTSK | |
| SCHEMBL6185853 | 0.82 | ALDH1A1 (0.53) | CTSLCTSB | |
| SCHEMBL6185845 | 0.82 | ALDH1A1 (0.53) | CTSLCTSB | |
| SCHEMBL6185000 | 0.81 | F10 (0.41) | CTSLCTSSCTSBCTSK | |
| SCHEMBL6185005 | 0.81 | F10 (0.41) | CTSLCTSSCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050282871-A1 | 3-(3,5-Disubstituted-4-hydroxyphenyl)propionamide derivatives as cathepsin b inhibitors | BURRILL II LELAND C | 2005-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050282871-A1 | 3-(3,5-Disubstituted-4-hydroxyphenyl)propionamide derivatives as cathepsin b inhibitors | CTSB, CTSZ, CTSS | CTSL 14/4885CTSS 3/4885CTSB 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.