Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6412941 | 0.86 | CA1 (0.57) | MAPTRAB9ACA12CA1CA2 | |
| SCHEMBL6408135 | 0.81 | KCNMA1 (0.55) | MEN1KMT2APOLBHSPA5 | |
| SCHEMBL6415342 | 0.77 | HSPA5 (0.47) | MAPTMEN1KMT2APOLBCA1 | |
| SCHEMBL6410312 | 0.77 | KCNMA1 (0.52) | KDM4ETDP1POLBHSPA5 | |
| SCHEMBL6410292 | 0.77 | HSPA5 (0.62) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL6409044 | 0.76 | KMT2A (0.50) | ALDH1A1MAPTKDM4ECYP1A2MEN1 | |
| SCHEMBL6416161 | 0.76 | MEN1 (0.52) | ALDH1A1MAPTKDM4ETDP1MEN1 | |
| SCHEMBL5726701 | 0.76 | TDP1 (0.66) | ALDH1A1MAPTKDM4ETDP1CYP1A2 | |
| SCHEMBL6414640 | 0.76 | ACLY (0.49) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL6413254 | 0.75 | MEN1 (0.52) | ALDH1A1MAPTTDP1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050124667-A1 | Oxamide inhibitors of plasminogen activator inhibitor-1 | CEREP SA (FR) | 2005-06-09 | — | — | US | claimed |
| US-20050124667-A1 | Oxamide inhibitors of plasminogen activator inhibitor-1 | CEREP SA (FR) | 2005-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124667-A1 | Oxamide inhibitors of plasminogen activator inhibitor-1 | SERPINE1, SERPINC1, SERPINB1 | ALDH1A1 360/4885MAPT 4191/4885KDM4E 2696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.