SCHEMBL6408632

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7162434	0.89	KDM4E (0.39)	ALDH1A1SMN1; SMN2METAP2NR1I2HTR3E
	SCHEMBL6408597	0.81	HRH4 (0.32)	ALDH1A1SMN1; SMN2KMT2AMEN1NPSR1
	SCHEMBL6407860	0.76	—	—
	SCHEMBL6406793	0.76	HTR1A (0.37)	DRD2DRD3
	SCHEMBL6409699	0.72	—	—
	SCHEMBL6413185	0.72	HTR3E (0.33)	ALDH1A1HTR3EHTR3BHTR3AHTR3D
	SCHEMBL25905716	0.72	DDB1 (0.48)	ALDH1A1SMN1; SMN2METAP2NR1I2KMT2A
	SCHEMBL6406945	0.70	—	—
	SCHEMBL25951320	0.70	ALDH1A1 (0.58)	ALDH1A1SMN1; SMN2METAP2KMT2AMEN1
	SCHEMBL179467	0.68	CA2 (0.50)	ALDH1A1SMN1; SMN2KMT2AMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.