SCHEMBL6408872

SCHEMBL6408872

CCCC1CCc2cc(-c3ccc(OCC)c(F)c3F)c(F)c(F)c2C1

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 2/20 0.32
PTGDR2 Q9Y5Y4 4/20 0.31
S1PR1 P21453 4/20 0.31
SGPL1 O95470 1/20 0.31
ESR1 P03372 1/20 0.31
S1PR2 O95136 1/20 0.31
S1PR4 O95977 1/20 0.31
S1PR3 Q99500 1/20 0.31
S1PR5 Q9H228 1/20 0.31
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13328589 0.83 ACHE (0.33) ACHE
SCHEMBL13328646 0.76 ALDH1A1 (0.34)
SCHEMBL1311479 0.75 RIPK1 (0.38) KDM1APTGDR2
SCHEMBL13328555 0.74 TLR4 (0.34) ACHE
SCHEMBL13378230 0.73 NPC1 (0.34) KDM1A
SCHEMBL31722819 0.73 NPC1 (0.34) KDM1A
SCHEMBL6402937 0.73 FYN (0.36) S1PR1SGPL1
SCHEMBL18084735 0.72 HTR1D (0.37) S1PR3
SCHEMBL12433700 0.72 KDM1A (0.32) KDM1AESR1
SCHEMBL11917052 0.72 FPR2 (0.35) KDM1AS1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050133762-A1 Liquid crystalline compound having high optical anisotropy and liquid crystalline composition comprising the same SAMSUNG ELECTRONIC CO., LTD. (KR) 2005-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050133762-A1 Liquid crystalline compound having high optical anisotropy and liquid crystalline composition comprising the same KIF23, CDK13, KIF11 KDM1A 3674/4885PTGDR2 3592/4885S1PR1 1860/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.