Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.41 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KCNMA1 | Q12791 | 7/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6409044 | 0.79 | KMT2A (0.50) | HSPA5MEN1KMT2AHPGDPOLB | |
| SCHEMBL6414640 | 0.79 | ACLY (0.49) | HSPA5MEN1KMT2APOLBKCNMA1 | |
| SCHEMBL6412962 | 0.77 | KMT2A (0.47) | HSPA5MEN1KMT2AHPGDKCNMA1 | |
| SCHEMBL6408135 | 0.77 | KCNMA1 (0.55) | HSPA5MEN1KMT2AHPGDPOLB | |
| SCHEMBL6414166 | 0.76 | CHRM3 (0.35) | HSP90AA1HSP90AB1HSPA5MEN1KMT2A | |
| SCHEMBL6409644 | 0.76 | HPGD (0.46) | MEN1KMT2AHPGDPOLBNPC1 | |
| SCHEMBL6407658 | 0.75 | CA1 (0.48) | HSPA5POLBKCNMA1MAPTMAPK1 | |
| SCHEMBL6408434 | 0.74 | MEN1 (0.50) | MEN1KMT2AHPGDKCNMA1NPC1 | |
| SCHEMBL6407747 | 0.74 | ALDH1A1 (0.56) | HSPA5MEN1KMT2APOLBNPC1 | |
| SCHEMBL6410312 | 0.72 | KCNMA1 (0.52) | HSPA5POLBKCNMA1STAT3ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050124667-A1 | Oxamide inhibitors of plasminogen activator inhibitor-1 | CEREP SA (FR) | 2005-06-09 | — | — | US | claimed |
| US-20050124667-A1 | Oxamide inhibitors of plasminogen activator inhibitor-1 | CEREP SA (FR) | 2005-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124667-A1 | Oxamide inhibitors of plasminogen activator inhibitor-1 | SERPINE1, SERPINC1, SERPINB1 | HSP90AA1 3508/4885HSP90AB1 3347/4885HSPA5 4261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.