Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT1 | P54687 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.36 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18493829 | 0.67 | BCAT1 (0.54) | BCAT1CYP2C9GPR27PTPN2PTPN1 | |
| SCHEMBL1098417 | 0.67 | LMNA (0.50) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6414471 | 0.65 | PTGES2 (0.41) | BCAT1CYP2C9GPR27PTPN2PTPN1 | |
| SCHEMBL1097665 | 0.64 | SLC40A1 (0.52) | SLC40A1NPSR1LMNASMN1; SMN2TSHR | |
| SCHEMBL4009030 | 0.64 | ACLY (0.38) | PTPN2PTPN1PTPN5MAPTMEN1 | |
| SCHEMBL7490626 | 0.58 | CA9 (0.41) | BCAT1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL27845644 | 0.58 | MEN1 (0.78) | CYP2C9PTPN2PTPN1PTPN5MAPT | |
| SCHEMBL1099660 | 0.57 | GAA (0.46) | MEN1KMT2ARXFP1KDM4EALDH1A1 | |
| SCHEMBL1094713 | 0.57 | KEAP1 (0.48) | SLC40A1MEN1HPGDKMT2AHSD17B10 | |
| SCHEMBL7847199 | 0.57 | CA2 (0.50) | MEN1HPGDKMT2AHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050026984-A1 | Substituted thieno [2,3-c] pyrazoles and their use as medicinal products | AVENTIS PHARMA S.A. (FR) | 2005-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050026984-A1 | Substituted thieno [2,3-c] pyrazoles and their use as medicinal products | TPMT, PARK7, PRNP | BCAT1 2316/4885CYP2C9 370/4885SLC40A1 2442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.