Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.51 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.51 |
| ▸ | TMPRSS4 | Q9NRS4 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.43 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.43 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6408135 | 0.84 | KCNMA1 (0.55) | CHRNA7MEN1KMT2AHSPA5KCNMA1 | |
| SCHEMBL3671992 | 0.83 | CHRNA7 (0.72) | CHRNA7MEN1KMT2ANTRK1CDK19 | |
| SCHEMBL6410312 | 0.82 | KCNMA1 (0.52) | CHRNA7HSPA5P2RX1KCNMA1 | |
| SCHEMBL6415342 | 0.80 | HSPA5 (0.47) | CHRNA7MEN1KMT2AHSPA5KCNMA1 | |
| SCHEMBL6410292 | 0.80 | HSPA5 (0.62) | MEN1KMT2AALDH1A1HSPA5 | |
| SCHEMBL6414640 | 0.78 | ACLY (0.49) | MEN1KMT2AALDH1A1HSPA5GPR35 | |
| SCHEMBL6407663 | 0.77 | NPC1 (0.50) | MEN1KMT2AALDH1A1HSPA5KCNMA1 | |
| SCHEMBL4349059 | 0.77 | GRIK1 (0.63) | CHRNA7MEN1KMT2ANTRK1CDK19 | |
| SCHEMBL1459621 | 0.77 | CHRNA7 (1.00) | CHRNA7MEN1KMT2ANTRK1CDK19 | |
| SCHEMBL6408459 | 0.76 | ACLY (0.59) | KCNMA1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050124667-A1 | Oxamide inhibitors of plasminogen activator inhibitor-1 | CEREP SA (FR) | 2005-06-09 | — | — | US | claimed |
| US-20050124667-A1 | Oxamide inhibitors of plasminogen activator inhibitor-1 | CEREP SA (FR) | 2005-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124667-A1 | Oxamide inhibitors of plasminogen activator inhibitor-1 | SERPINE1, SERPINC1, SERPINB1 | CHRNA7 4742/4885MEN1 1009/4885KMT2A 3936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.